Protein Alignment Ns3 and C53H9.2

DIOPT Version :9

• Sequence 1: NP_001284779.1
• Gene: Ns3 / 31097
• FlyBaseID: FBgn0266284
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_740787.2
• Gene: C53H9.2 / 171749
• WormBaseID: WBGene00016907
• Length: 554
• Species: Caenorhabditis elegans
• Alignment Length: 628
• Identity: 240/628 - (38%)
• Similarity: 345/628 - (54%)
• Gaps: 112/628 - (17%)

  Fly     3 KKNKGGAPNLGRQLIKD----RFGHTQRRKVDNDTMLHTTELQDGYDWGRLN--LSSVTEESSFQ 61
            ||..|...:||..|..|    |..| ||.|.|.:.:.:...::.     .:|  :.|||:|:|.:
 Worm     9 KKPSGLNKSLGNSLSNDREKTRKSH-QRAKYDGNDIENPAFMEH-----EVNHYIDSVTDETSLE 67

  Fly    62 AFLRTAELAGTEFQAEKLNITFVNPKQRVGLLSKTQEQRMH---QKHDEHRDQLKIPRRPKWTKE 123
            .||..||||||||.|||.....:.....: ::....:.|.:   ||.:|||  |:|||||.....
 Worm    68 EFLAKAELAGTEFTAEKEQFKIIEKNSAI-VVPTRLDYRANLDLQKENEHR--LRIPRRPAKELW 129

  Fly   124 TSAEELVRAENEAFLDWRRDLALLQEDEEILMTPYEKNLEFWRQLWRVVERSDVVVQIVDARNPL 188
            .:.|:|.:.||||||.||.||:.|||.:.:::||:|:|.:.||:||||||:||::||||||||||
 Worm   130 ENMEDLTKLENEAFLQWRSDLSELQEVDGLVLTPFERNPDMWRELWRVVEKSDIIVQIVDARNPL 194

  Fly   189 LFRSADLERYVKEVEPSKMNMILVNKSDLLTEEQRRHWAEYFDSEGIRTAFYSATLVEEELKREA 253
            ||||.||:.|||||:|:|..::||||:|||..||:..|.|||:.|.|:..|:|
 Worm   195 LFRSKDLDDYVKEVDPAKQILLLVNKADLLKPEQQASWREYFEKENIKVIFWS------------ 247

  Fly   254 EECLDSFPEVQQLRRAVEEIKQSLDSVEDALNVIEQKYKTIPETQNDELPRLPGDKNSPRLLSRL 318
                           |::|:...:|  |||:           ||.|      |.......:.::.
 Worm   248 ---------------AIDEVLDPID--EDAV-----------ETSN------PSTSTHMFVTNKD 278

  Fly   319 ELIEFLRNI-YTGPRHTEQHVTVGMVGYPNVGKSSTINSLMTVKKVSVSATPGKTKRFQTLFLDK 382
            |||...:.: :.....:.:.|.||||||||||||||||.|...||||||||||||:.|||:.:|.
 Worm   279 ELIAKFKELGHVSDEPSAKPVMVGMVGYPNVGKSSTINKLAGGKKVSVSATPGKTRHFQTIHIDS 343

  Fly   383 DILLCDCPGLVMPSFVLTKADMLLNGILPIDQMRDHVPAVNLLCERIPRHVLEDKYGIVIAKPLE 447
            .:.||||||||||||...:::|.||||||:||||||....:||..|:|.||:|..|.|::.:
 Worm   344 QLCLCDCPGLVMPSFSFGRSEMFLNGILPVDQMRDHFGPTSLLLSRVPVHVIEATYSIMLPE--- 405

  Fly   448 GEDMERPPHSEELLLAYGYNRGFMTSNGQPDQARSARYVLKDYVNGRLLYAMSPPSVPQTEYH-- 510
                .:.|.:..||.:..:.||||.|:|.||.:|:||.:.||.|:|:|::|.:||.|.|.|:.
 Worm   406 ----MQSPSAINLLNSLAFMRGFMASSGIPDCSRAARLMFKDVVSGKLIWAAAPPGVEQEEFDRI 466

  Fly   511 TFPERQRR--------------VIEESQLPGQQQRAMRINKSTSKELDNQFFSDKPTHAHVKGRT 561
            ::|:::.|              ::|..:|.|.|             .|:|.|......|||:...
 Worm   467 SYPDKKTRDIGRVQMEKLAKLQLLEGDELKGSQ-------------FDSQHFVGSIGVAHVRDSK 518

  Fly   562 NFPNVRLANDGSLVAGNDPAAKPWRHVKKE---RREKLRKKFS 601
            ..|...    |:::    |.|....:.||.   :::|||:.::
 Worm   519 ALPQTL----GTVI----PTAPTENNGKKHYKGKKDKLRRIYN 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_001284779.1	RbgA	161..524	CDD:224083	160/379 (42%)
		HSR1_MMR1	164..395	CDD:206750	105/231 (45%)
		p10	<270..312	CDD:177631	9/41 (22%)
		P-loop_NTPase	313..>357	CDD:304359	20/44 (45%)
C53H9.2	NP_740787.2	RbgA	145..476	CDD:224083	169/383 (44%)
		HSR1_MMR1	171..356	CDD:206750	105/230 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162530
Domainoid	1	1.000	199	1.000	Domainoid score	I1791
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5917
Inparanoid	1	1.050	372	1.000	Inparanoid score	I1221
Isobase	1	0.950	-	0	Normalized mean entropy	S1757
OMA	1	1.010	-	-		QHG55394
OrthoDB	1	1.010	-	-		D206558at33208
OrthoFinder	1	1.000	-	-		FOG0004203
OrthoInspector	1	1.000	-	-		oto17665
orthoMCL	1	0.900	-	-		OOG6_101986
Panther	1	1.100	-	-	LDO	PTHR45709
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2947
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.860