Protein Alignment Ns3 and Gnl1

DIOPT Version :9

• Sequence 1: NP_001284779.1
• Gene: Ns3 / 31097
• FlyBaseID: FBgn0266284
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: XP_036016217.1
• Gene: Gnl1 / 14670
• MGIID: 95764
• Length: 730
• Species: Mus musculus
• Alignment Length: 625
• Identity: 180/625 - (28%)
• Similarity: 269/625 - (43%)
• Gaps: 111/625 - (17%)

  Fly    14 RQLIKDRFGHTQRRKVDNDT------MLHTTELQD---------GYDWGRLNL----SSVTEESS 59
            |.....|.|..:||:...||      ..|...|..         |||..|..|    .|..|...
Mouse   154 RSSSNSRSGSRERREEQTDTSDGESVTHHIRRLNQQPSQGLGPRGYDPNRYRLHFERDSREEVER 218

  Fly    60 FQAFLRTAELAGTEFQAEKLNITFVNPKQRVGLLSKTQEQRMHQKHDEHRDQLKIPRRPKWTKET 124
            .:...|...|.....:..:|:|..|.....|                     |..||||.|:.|.
Mouse   219 RKRAAREQVLQPVSAEVLELDIREVYQPGSV---------------------LDFPRRPPWSYEM 262

  Fly   125 SAEELVRAENEAFLDWRRDLALLQEDEEILMTPYEKNLEFWRQLWRVVERSDVVVQIVDARNPLL 189
            |.|:|:..|..:|.::...:......|:  ::.:|.|||.|||||||:|.||:|:.|.|.|:|::
Mouse   263 SKEQLMSQEERSFQEYLGKIHGAYTSEK--LSYFEHNLETWRQLWRVLEMSDIVLLITDIRHPVV 325

  Fly   190 FRSADLERYVKEVEPSKMNMILV---NKSDLLTEEQRRHWAEYFDS------EGIRTAFYSATLV 245
            .....|..||    ..::.:.||   ||.||........|..||..      ..:.|:|...|..
Mouse   326 NFPPALYEYV----TGELGLALVLVLNKVDLAPPALVVAWKHYFHQCYPQLHIVLFTSFPRDTRT 386

  Fly   246 EEE----LKREAE------ECLDSFPEVQQLRRAVEEI---KQSLDSVED--ALNVIEQKYKTIP 295
            .:|    ||:...      ..|.  ||  ||.||.|.|   |..|.|..:  |.:|....:..:.
Mouse   387 PQEPGGVLKKNRRRGKGWTRALG--PE--QLLRACEAITVGKVDLSSWREKIARDVAGASWGNVS 447

  Fly   296 ETQNDELPRLPGDKNSPRLLSRLELIEFLRNIY---TGP---RHTEQHVTVGMVGYPNVGKSSTI 354
            ..:.:|       ::.|.:     |:|.|.:..   |||   |:.:..||:|.:|:|||||||.|
Mouse   448 GEEEEE-------EDGPAV-----LVEQLTDSAMEPTGPSRERYKDGVVTIGCIGFPNVGKSSLI 500

  Fly   355 NSLMTVKKVSVSATPGKTKRFQTLFLDKDILLCDCPGLVMPSFVLTKADMLLNGILPIDQMRDHV 419
            |.|:..|.||||.|||.|:.|||.||...:.|||||||:.|| :|.:...:|.||.||.|:::..
Mouse   501 NGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLIFPS-LLPRQLQVLAGIYPIAQIQEPY 564

  Fly   420 PAVNLLCERIPRHVLEDKYGIVIAKPLEGED--MERPPHSEELLLAYGYNRGFMTSN-GQPDQAR 481
            .:|..|..|||...|     :.:..| |.||  .|.|..:.::..|:...||:.|:. .:.|..|
Mouse   565 TSVGYLASRIPVQAL-----LHLRHP-EAEDPSAEHPWCAWDICEAWAEKRGYKTAKAARNDVYR 623

  Fly   482 SARYVLKDYVNGRLLYAMSPP--SVPQTEYHTFPERQRRVIEESQL--PGQQQRAMRINKSTSKE 542
            :|..:|:..|:|||.....||  |..:..:.:.||....|:.:.::  .|.::.......|:|.|
Mouse   624 AANSLLRLAVDGRLSLCFYPPGYSEQRGTWESHPETAELVLSQGRVGPAGDEEEEEEEELSSSCE 688

  Fly   543 LDNQFFSDKPTHAHVKGRTNFPNVRLANDGSLVAGNDPAA 582
            .:.:  .|:......:|..:.|.   ::.||.:...:|.|
Mouse   689 EEGE--EDRDADEEGEGDEDTPT---SDPGSCLTARNPYA 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_001284779.1	RbgA	161..524	CDD:224083	133/397 (34%)
		HSR1_MMR1	164..395	CDD:206750	91/260 (35%)
		p10	<270..312	CDD:177631	8/46 (17%)
		P-loop_NTPase	313..>357	CDD:304359	20/49 (41%)
Gnl1	XP_036016217.1	RbgA	293..637	CDD:224083	126/370 (34%)
		HSR1_MMR1	300..541	CDD:206750	91/260 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55394
OrthoDB	1	1.010	-	-		D206558at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830