Protein Alignment Ns3 and lsg1

DIOPT Version :9

• Sequence 1: NP_001284779.1
• Gene: Ns3 / 31097
• FlyBaseID: FBgn0266284
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: XP_002937880.1
• Gene: lsg1 / 100145528
• XenbaseID: XB-GENE-990730
• Length: 637
• Species: Xenopus tropicalis
• Alignment Length: 654
• Identity: 317/654 - (48%)
• Similarity: 417/654 - (63%)
• Gaps: 68/654 - (10%)

  Fly     1 MGKKNKGGAPNLGRQLIKDRFGHTQRRKVDNDTMLHTTELQDGYDWGRLNLSSVTEESSFQAFLR 65
            ||||.  ....|||.|||:| ..:||.....|:.|||:||.||||||||||.||||:||...||.
 Frog     1 MGKKK--ATCGLGRALIKER-AQSQRGLRAKDSWLHTSELNDGYDWGRLNLQSVTEQSSIDDFLA 62

  Fly    66 TAELAGTEFQAEKLNITFVNPKQRVGLLSKTQEQRMHQKHDEHRDQLKIPRRPKWTKETSAEELV 130
            |||||||||.||||||.||:.:.|..||:..:.:|:|:..:|::..|.|||||.|.:.||||.|.
 Frog    63 TAELAGTEFVAEKLNIKFVSAEARTELLTSEETKRIHKLQEENKQFLCIPRRPHWDESTSAEVLR 127

  Fly   131 RAENEAFLDWRRDLALLQEDEEILMTPYEKNLEFWRQLWRVVERSDVVVQIVDARNPLLFRSADL 195
            ..|.|.||.|||.||.|:|::::::||:|:||:||||||||:|||||||||||||||||||..||
 Frog   128 ETERETFLQWRRQLAQLEEEKKLILTPFERNLDFWRQLWRVIERSDVVVQIVDARNPLLFRCQDL 192

  Fly   196 ERYVKEVEPSKMNMILVNKSDLLTEEQRRHWAEYFDSEGIRTAFYSATLVEEELKREAE-ECLD- 258
            |.||||::..|.|:||:||:||||.:||:.|||:|:.||::..|:||....:.|..|.: |.||
 Frog   193 ECYVKEIDKDKENIILINKADLLTAQQRQSWAEFFEKEGVKVVFWSALAEGQRLTAEGKVEHLDE 257

  Fly   259 ------SFPEVQQLRRAVEEIK---------QSLDS-----VEDALNVIEQKYKTIPE------- 296
                  .|.:.::.....||.:         ..||:     .||...  ::.::|..|
 Frog   258 IKENEGDFTDEEESESESEETQGENLHTRGNSGLDNDTSEEYEDCEE--DEGWQTCSEDADDDDI 320

  Fly   297 -TQNDELPRLPGDK---NSPRLLSRLELIEFLRNIYTGPRHTEQHVTVGMVGYPNVGKSSTINSL 357
             :|:.:..|..|||   |...|:.|.||:|..::::.|.|..|..:|||:|||||||||||||::
 Frog   321 ISQDKDHTRTVGDKLITNQSHLVERDELLEIFKSVHAGQRIKEGQITVGLVGYPNVGKSSTINTI 385

  Fly   358 MTVKKVSVSATPGKTKRFQTLFLDKDILLCDCPGLVMPSFVLTKADMLLNGILPIDQMRDHVPAV 422
            :..||||||||||.||.||||::::::.|||||||||||||.|||:|:.:|||||||||||||.:
 Frog   386 LGNKKVSVSATPGHTKHFQTLYVEQELCLCDCPGLVMPSFVSTKAEMICSGILPIDQMRDHVPPI 450

  Fly   423 NLLCERIPRHVLEDKYGIVIAKPLEGEDMERPPHSEELLLAYGYNRGFMTSNGQPDQARSARYVL 487
            :|:.:|||||.||..|||.|.:|.|.||.:|||.|||.|.||||.|||||::|||||.|||||||
 Frog   451 SLIAQRIPRHALETIYGINIIRPREDEDQDRPPTSEEFLCAYGYMRGFMTAHGQPDQPRSARYVL 515

  Fly   488 KDYVNGRLLYAMSPPSVPQTEYHTFPERQRRVIEES---QLPGQQQRAMRINKSTSKE--LDNQF 547
            ||||:|:|||...||.:...|:    :.|....||.   ::.|:.| |.|..|:...|  :|..|
 Frog   516 KDYVSGKLLYCHPPPGIEPAEF----QPQFVKYEEKKGLKISGESQ-AHRGKKTRQIENVVDTNF 575

  Fly   548 FSDKPTHAHVKGRTNFPNVRLANDGSLVAGNDP-----------AAKPW-RHVKKERREKLRKKF 600
            |..:...|..||..:....:        .|:.|           |.||| :|..|.::||:|:..
 Frog   576 FHQENVRALTKGVQSVMGYK--------PGSGPVPLYATSLDTVAGKPWKKHGNKNKKEKIRRLN 632

  Fly   601 SHLD 604
            .|||
 Frog   633 KHLD 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns3	NP_001284779.1	RbgA	161..524	CDD:224083	205/398 (52%)
		HSR1_MMR1	164..395	CDD:206750	123/263 (47%)
		p10	<270..312	CDD:177631	14/66 (21%)
		P-loop_NTPase	313..>357	CDD:304359	24/43 (56%)
lsg1	XP_002937880.1	RbgA	136..547	CDD:224083	214/416 (51%)
		HSR1_MMR1	161..423	CDD:206750	123/263 (47%)
		P-loop_NTPase	345..>387	CDD:304359	23/41 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	298	1.000	Domainoid score	I1436
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5917
Inparanoid	1	1.050	457	1.000	Inparanoid score	I1535
OMA	1	1.010	-	-		QHG55394
OrthoDB	1	1.010	-	-		D206558at33208
OrthoFinder	1	1.000	-	-		FOG0004203
OrthoInspector	1	1.000	-	-		oto102957
Panther	1	1.100	-	-	LDO	PTHR45709
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2947
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080