Protein Alignment CG14787 and CDYL

DIOPT Version :10

• Sequence 1: NP_569914.2
• Gene: CG14787 / 31096
• FlyBaseID: FBgn0027793
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001355054.1
• Gene: CDYL / 9425
• HGNCID: 1811
• Length: 598
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 52/220 - (23%)
• Similarity: 91/220 - (41%)
• Gaps: 46/220 - (20%)

  Fly     5 ESCKHFRELVVEQRSGLLHIRFQRRWQR------RTLYELMRALDLASADAAVKVVVLSGEFSAA 63
            ||...:|::||.::.|..||....:...      ..:.|:..||..|:||.: |:|:||...|..
Human   336 ESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAADDS-KLVLLSAVGSVF 399

  Fly    64 CGGEMEPLALKQGLENRSRRTASHEEAVGSGDAEEQYIHEKAANFVMRSLAKKLLVHRKLLVAFV 128
            |.|......:::..::|.|.:....||:                   |:.....:..:|.::..|
Human   400 CCGLDFIYFIRRLTDDRKRESTKMAEAI-------------------RNFVNTFIQFKKPIIVAV 445

  Fly   129 ERQCVGLGLSVCSLCDLVFATELSAFVPAFSHL----DPCTKVGPGWTVPHV------HWLLRLG 183
            ....:|||.|:..|||:|:|.|.:.|...::..    |.|:.|    ..|.:      :.:|..|
Human   446 NGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTV----MFPKIMGGASANEMLLSG 506

  Fly   184 DQASSSIALQCGLVASVVREPQEFW 208
            .:.::..|...|||:.|      ||
Human   507 RKLTAQEACGKGLVSQV------FW 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14787	NP_569914.2	crotonase-like	13..216	CDD:474030	49/212 (23%)
CDYL	NP_001355054.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..76
		Interaction with EZH2. /evidence=ECO:0000269|PubMed:22009739	61..309
		CD_CDY	62..111	CDD:349284
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	112..149
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..226
		crotonase-like	344..540	CDD:119339	49/212 (23%)
		Acetyl-CoA-binding domain. /evidence=ECO:0000255	362..594		44/194 (23%)