Protein Alignment CG14787 and ECHDC2

DIOPT Version :10

• Sequence 1: NP_569914.2
• Gene: CG14787 / 31096
• FlyBaseID: FBgn0027793
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001185890.1
• Gene: ECHDC2 / 55268
• HGNCID: 23408
• Length: 292
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 59/276 - (21%)
• Similarity: 92/276 - (33%)
• Gaps: 77/276 - (27%)

  Fly    20 GLLHIRFQRRWQRRTL-----YELMRALDLASADAAVKVVVL-SGEFSAACGGEMEPLALKQGLE 78
            |:..|...|...|..|     .||:..|.....|..|:|::. ||.....|.|    ..||:
Human    41 GITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAG----ADLKE--- 98

  Fly    79 NRSRRTASHEEAVGSGDAEEQYIHEKAANFV--MRSLAKKLLVHRKLLVAFVERQCVGLGLSVCS 141
                              .||....:...||  :|.|...:.......:|.::...:|.||.:..
Human    99 ------------------REQMSEAEVGVFVQRLRGLMNDIAAFPAPTIAAMDGFALGGGLELAL 145

  Fly   142 LCDLVFA--TELSAFVPAFSHLDPCTKVGPGWT--------VPHVHWLLRLGDQASSSIALQCGL 196
            .|||..|  :.:...:.....|.|    |.|.|        |.....|:..|.:.|.:.|...||
Human   146 ACDLRVAASSAVMGLIETTRGLLP----GAGGTQRLPRCLGVALAKELIFTGRRLSGTEAHVLGL 206

  Fly   197 VASVVREPQE---FWHR----------------------VDQYLRLPSASLLATKRLLFR---PW 233
            |...|.:.:|   .:.|                      :|:...:..||.:|.:.:.:.   |.
Human   207 VNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNIPT 271

  Fly   234 QDSL--LAELREEGTP 247
            :|.|  :|..||:.||
Human   272 RDRLEGMAAFREKRTP 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14787	NP_569914.2	crotonase-like	13..216	CDD:474030	48/238 (20%)
ECHDC2	NP_001185890.1	crotonase-like	38..292	CDD:474030	59/276 (21%)