DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lrpprc2 and LOJ

DIOPT Version :9

Sequence 1:	NP_569913.1	Gene:	Lrpprc2 / 31095	FlyBaseID:	FBgn0027794	Length:	1072	Species:	Drosophila melanogaster
Sequence 2:	NP_181456.1	Gene:	LOJ / 818508	AraportID:	AT2G39230	Length:	867	Species:	Arabidopsis thaliana

Alignment Length:	645	Identity:	121/645 - (18%)
Similarity:	223/645 - (34%)	Gaps:	156/645 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLRNVWLCRQRLGHLPGRSASSASL------------AFRYATKPAAPAVPFSLLQMRSLGTG-- 56
            |||.:   |.:|| :|....:..|:            |.|...:.....:|.|::...||..|
plant   296 LLREM---RGKLG-VPASQETYTSVIVAFVKEGNMEEAVRVMDEMVGFGIPMSVIAATSLVNGYC 356

  Fly    57 -----GVLSAVERRSRRPASSSEKPKASVADAW--------TQLEAYYRQHDLINFEHCQRLLEL 108
                 |....:..|......:.:|...||...|        ..:|.|.|...:
plant   357 KGNELGKALDLFNRMEEEGLAPDKVMFSVMVEWFCKNMEMEKAIEFYMRMKSV------------ 409

  Fly   109 LQESASPLGVGIEEVHFLLGSCVPELLPAQSSQERLQLFKGLWAQLIKLGQPTLAHYHTKLQVL- 172
               ..:|..|   .||.::..|    |.|:|.:..|::|...:...|..|     ....|:.:|
plant   410 ---RIAPSSV---LVHTMIQGC----LKAESPEAALEIFNDSFESWIAHG-----FMCNKIFLLF 459

  Fly   173 -RQNRL-PLTDYRSLLAEIAVYHGAADSTLYGALLDVAGAAGNMRMATEILSEMRERSLALTEHN 235
             :|.:: ..|.:..::.:..:   ..:...|..::.......||.:|..|.|||.|:.|......
plant   460 CKQGKVDAATSFLKMMEQKGI---EPNVVFYNNMMLAHCRMKNMDLARSIFSEMLEKGLEPNNFT 521

  Fly   236 FHALLLGHARSGDLPGAESVLASMRAAGIQQGSSTQAIWFEALLENGQLAQAKELLQ-----VEH 295
            :..|:.|..::.|...|..|:..|.|:..:............|.:.||.::|||:||     ..:
plant   522 YSILIDGFFKNKDEQNAWDVINQMNASNFEANEVIYNTIINGLCKVGQTSKAKEMLQNLIKEKRY 586

  Fly   296 GFTAPQLLQMLRGLLASKDVDTDLIQLLVKELPREFLTGIDLPPAI--RSLCIQLVHQGRTEVVI 358
            ..:......::.|.:...|.|:.:      |..||.......|..:  .||........|.::.:
plant   587 SMSCTSYNSIIDGFVKVGDTDSAV------ETYREMSENGKSPNVVTFTSLINGFCKSNRMDLAL 645

  Fly   359 QLVGALPAPKFELQNQNVDEYGALLLQEFFRAQVPLDQTIQFAGQLVQRNQNVRALHLVAELALR 423
            ::...:.:.:.:|   ::..||||:                  ....::|....|..|.:||
plant   646 EMTHEMKSMELKL---DLPAYGALI------------------DGFCKKNDMKTAYTLFSEL--- 686

  Fly   424 RQPSSALRCLEDLSAAGEELRPHYFWPLILHHYRREGE-SGMLRLVSEMRRLRVECDEETLRHYL 487
              |...|  :.::|.          :..::..:|..|: ...:.|..:|....:.||       |
plant   687 --PELGL--MPNVSV----------YNSLISGFRNLGKMDAAIDLYKKMVNDGISCD-------L 730

  Fly   488 FPHLRQTLVQPL----------EAVKALESAGVKPSQTLCPVV-------SHLLQQHQMSEVLDL 535
            |.:  .|::..|          :....|...|:.|.:.|..|:       ...|:..:|.|.:..
plant   731 FTY--TTMIDGLLKDGNINLASDLYSELLDLGIVPDEILHMVLVNGLSKKGQFLKASKMLEEMKK 793

  Fly   536 LDRYPTRLDLATLLQPLSSLAVNARATKRFEVFAKVIQALQQKALKRG---EDFVGSLLL 592
            .|..|..|..:|:      :|.:.|.....|.|     .|..:.|::|   :|.|.:||:
plant   794 KDVTPNVLLYSTV------IAGHHREGNLNEAF-----RLHDEMLEKGIVHDDTVFNLLV 842

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lrpprc2	NP_569913.1	PLN03218	<197..>292	CDD:215636	23/94 (24%)
		PPR repeat	201..227	CDD:276811	8/25 (32%)
		PPR repeat	233..262	CDD:276811	6/28 (21%)
		PPR repeat	268..292	CDD:276811	6/23 (26%)
LOJ	NP_181456.1	PPR	170..202	CDD:273253
		PPR repeat	171..198	CDD:276811
		PPR_2	208..248	CDD:289786
		PPR repeat	208..233	CDD:276811
		PPR repeat	239..268	CDD:276811
		PPR_2	312..357	CDD:289786	8/44 (18%)
		PPR	312..341	CDD:279828	3/28 (11%)
		PPR repeat	312..339	CDD:276811	3/26 (12%)
		PPR_2	344..392	CDD:289786	10/47 (21%)
		PPR repeat	345..374	CDD:276811	5/28 (18%)
		PPR	349..379	CDD:273253	5/29 (17%)
		PPR_2	378..427	CDD:289786	12/70 (17%)
		PPR repeat	380..408	CDD:276811	7/27 (26%)
		PPR	381..415	CDD:273253	7/48 (15%)
		PPR repeat	415..440	CDD:276811	9/31 (29%)
		PPR	450..484	CDD:273253	4/36 (11%)
		PPR repeat	451..478	CDD:276811	4/26 (15%)
		PPR_2	452..496	CDD:289786	5/46 (11%)
		PPR_2	482..531	CDD:289786	12/48 (25%)
		PPR repeat	486..513	CDD:276811	8/26 (31%)
		PPR	487..518	CDD:273253	10/30 (33%)
		PPR_1	513..545	CDD:289614	6/31 (19%)
		PPR repeat	519..548	CDD:276811	6/28 (21%)
		PPR_1	549..577	CDD:289614	6/27 (22%)
		PPR repeat	556..584	CDD:276811	8/27 (30%)
		PPR_2	592..637	CDD:289786	9/50 (18%)
		PPR	592..625	CDD:273253	7/38 (18%)
		PPR repeat	592..619	CDD:276811	6/32 (19%)
		PPR_1	619..652	CDD:289614	4/32 (13%)
		PPR_2	623..672	CDD:289786	9/69 (13%)
		PPR repeat	627..654	CDD:276811	3/26 (12%)
		PPR repeat	660..689	CDD:276811	10/51 (20%)
		PPR_2	693..742	CDD:289786	11/67 (16%)
		PPR repeat	695..724	CDD:276811	5/38 (13%)
		PPR	697..729	CDD:273253	4/41 (10%)
		PPR_2	729..777	CDD:289786	10/56 (18%)
		PPR repeat	730..758	CDD:276811	5/29 (17%)
		PPR	731..765	CDD:273253	6/35 (17%)
		PPR repeat	765..794	CDD:276811	5/28 (18%)
		PPR_1	794..826	CDD:289614	9/42 (21%)
		PPR_2	798..844	CDD:289786	14/56 (25%)
		PPR repeat	800..829	CDD:276811	8/39 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I2075
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050