Protein Alignment Lrpprc2 and lrpr-1

DIOPT Version :10

• Sequence 1: NP_569913.1
• Gene: Lrpprc2 / 31095
• FlyBaseID: FBgn0027794
• Length: 1072
• Species: Drosophila melanogaster
• Sequence 2: NP_001412560.1
• Gene: lrpr-1 / 178978
• WormBaseID: WBGene00015425
• Length: 996
• Species: Caenorhabditis elegans
• Alignment Length: 1072
• Identity: 184/1072 - (17%)
• Similarity: 323/1072 - (30%)
• Gaps: 405/1072 - (37%)

  Fly    60 SAVERRS--RRPASSSEKPKASVADA-----WTQLEAYYR-QHDLINFEHCQRLLELLQESASPL 116
            |.:.||.  |...:|.||.:||..|.     ...|...|| ..|:|.|:..:::....|.....:
 Worm    43 SKLVRRGDFRGVVASKEKNRASNPDVVLSRIQENLRKNYRISGDVILFDVVRQMESGNQNFIDHV 107

  Fly   117 GVGIEE-VHFLLGSCVPELLPAQSSQERLQLFKGLWAQL-IKLGQPTLAHYHTKLQVLRQNRL-- 177
            ....|. :..|:..|...|...:::.:. ::.:.||||| .||.:..:..::.:.|||.:|.:
 Worm   108 VRSPERWIPMLIHGCGHSLSNIETASKN-EILERLWAQLQSKLAKVPVYAWNARFQVLNENEVDW 171

  Fly   178 -PLTDYRSLLAEIAVYHGAADSTLYGALLDVAGAAGNMRMATEILSEMRERSLALTEHNFHALLL 241
             ||.:                                       |..|....:..|...|||::.
 Worm   172 DPLKE---------------------------------------LDNMERSGVEPTIETFHAVVK 197

  Fly   242 GHARSGDLPGAESVLASMRAAGIQQGSSTQA------------IWFEALLENGQLAQAKELLQVE 294
            ..:.|||:.|.::::.:|...|....:...|            :..::|.|.......:|..|:.
 Worm   198 RISASGDVDGCKNMVYNMARKGFSVDAHINAASVFAFSIRGHYLKADSLCEQASTKYGEEGSQLA 262

  Fly   295 HGFTA---------PQLLQMLRG---------LLASKDV-------------------------- 315
            ||...         .:|.|:||.         .|:|.|:
 Worm   263 HGAAVRAAACRGDNDRLRQVLRKSVIGSTKKLFLSSTDILETIWQMAEKSRDGKGAECSQLVEQM 327

  Fly   316 ------DTDLIQLLVKEL-----PREFLTGIDLPPAIRSLCIQLVHQGRTEVVIQLVGAL----- 364
                  |:...:.|.:|:     .|.:.|.:.|....:.:...|.:|.:...:.||||.|
 Worm   328 LNCTLRDSGFFRKLFREIERHICSRHYYTALSLLEDTKRVSDCLENQRKNAFLHQLVGRLSTQLI 392

  Fly   365 ----PA---------PKFELQNQ----NVDEYGALLLQEFFRAQVPLDQTIQFAGQLVQRNQNVR 412
                ||         ..|...|:    .:..|..||........:.||..:::....|......|
 Worm   393 RSHEPAHLIRDIANRVHFTFNNKYSKLKIRMYDDLLFATLMLKDMDLDDRLRYFRSFVDEIDTRR 457

  Fly   413 -ALHLVAELALRRQP-SSALRCLEDLSAAGEE--------------LRPHY-------------- 447
             .:|:...|....|. ...|..|..||..|..              |:|.|
 Worm   458 ERIHITLPLMTSEQNLDQRLAILYRLSTMGYRDWSSIENEPLVQIILQPLYNSGRPFRNQSKLDK 522

  Fly   448 --------------FWPLILHHYRREGESGMLRLVSEMRRLRVECDEETLRHY------------ 486
                          .| :|||.:.::          :.::...:.:|:..|.|
 Worm   523 LARILKSYGISERQVW-MILHRWSKQ----------KAKQEAPQPEEQWSRPYAKDLRGWCRAYY 576

  Fly   487 --LFPHLRQTLVQ----PLEAVKALESAG--VKPSQTLCPVVSHLLQQHQMSEVLDLLDRYPTRL 543
              .|...:.|:..    |.|.:|:....|  .|.|..||.                  :.:|...
 Worm   577 SETFESPKTTMNNSIPIPYEKLKSCVDQGDITKVSSVLCS------------------NGWPVDT 623

  Fly   544 DLATLLQPLSSLAVNARATKRFEVFAKVIQALQQKALKRGEDFVGSLLLQMTGPQTRLRQDATSL 608
            |...::.|:.:|.:      ..|.:..|...|::.|...||                ..:|.:.
 Worm   624 DFGEIVPPVLNLYL------MHESWKNVRSMLEEIAAFSGE----------------WNEDPSK- 665

  Fly   609 RRFLHELRRLELQISPAASEALLSVVRHATDDVD-----LIQDLAKTLQKMKNPQLALPADTVSL 668
                          ||..:..||||:|...::.|     .|.|.|..|:.:      .|..|...
 Worm   666 --------------SPMKNFHLLSVLRRMAEEEDTLSIRAITDYAYELRTL------FPHATCYY 710

  Fly   669 HG----------------------GFIKHPRDMSIDELECHLVELESKQLNPR------------ 699
            .|                      |......|..||.|.| ||:|:..||:|.
 Worm   711 EGFFETQTEYKKLFVKCFERLERQGLTTSTVDELIDFLRC-LVKLDLIQLHPSESLTVFFINILL 774

  Fly   700 --------------------------GVLRRLLQLSVRSGR------LERAQQLLAKCQVLKVQE 732
                                      .:||..||.:....|      |.|....|::.:
 Worm   775 KRLGWAEALSTWQKFLSSLHCPNGTVALLRHCLQQNTDEARMNLQFVLHRGSTFLSQSR------ 833

  Fly   733 SAGMMASIFDLHIKLRDLPRAQESLERLS---------------SMYPAFQIDEHKVIDYAALLV 782
               |.|..|.:.|.:|....|::..::||               :...|..:|:..::|:|||.:
 Worm   834 ---MSAMHFAVLISMRKFEDAEKFCDQLSHKVDPNDCLMAMRLMNSLKARSVDDQFMLDFAALCL 895

  Fly   783 QGQQLEAAKQLLQRRAEQHKVVGGDYVMKNVWQLLTNVGQLAASSHAGGESSKQLNQTREWLDFL 847
            :...|...|::.|                   .:..::.::..:.|.|..:.:..:...|:
 Worm   896 RKLGLSDNKEVAQ-------------------SMQADLLRICDTRHMGPTALRVYDLFSEY---- 937

  Fly   848 RGLGYCQSQNALLGPVV-------REWLLKGN 872
             |:...:.:...|..|:       ::|:.|.|
 Worm   938 -GVELREEEKNRLAAVIEKHSTLSKKWIFKPN 968

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lrpprc2	NP_569913.1	PLN03218	<197..>292	CDD:215636	16/106 (15%)
		PPR repeat	201..227	CDD:276811	2/25 (8%)
		PPR repeat	233..262	CDD:276811	8/28 (29%)
		PPR repeat	268..292	CDD:276811	4/35 (11%)
lrpr-1	NP_001412560.1	PPR repeat	189..218	CDD:276811	8/28 (29%)
		PPR repeat	224..249	CDD:276811	2/24 (8%)