Protein Alignment CG14785 and Klhl5

DIOPT Version :10

• Sequence 1: NP_569912.2
• Gene: CG14785 / 31094
• FlyBaseID: FBgn0027795
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_780383.2
• Gene: Klhl5 / 71778
• MGIID: 1919028
• Length: 708
• Species: Mus musculus
• Alignment Length: 317
• Identity: 50/317 - (15%)
• Similarity: 126/317 - (39%)
• Gaps: 75/317 - (23%)

  Fly    65 KPEPEKLESGAQGDAGSASSTSAHAVKLLPIEGDPAKLKAL--TSRQQIASLLNHLGDGAEGDGE 127
            :||.:...|..:.::.|:||.::::.:.|      :..:|:  .|..:....|||
Mouse   107 RPEVDDGTSEEENESDSSSSRTSNSSQTL------SSCQAMEPCSSDEFFQALNH---------- 155

  Fly   128 AKQIVMELLGSGVQPHSAIERVSEQLLHVLREQTLMEAGIFVGNERYRFFKGVLQNYAKIYAA-- 190
                              .|:..:::.:.||.:.|.:..:..|:.|....:.||.:.:..:||
Mouse   156 ------------------AEQTFKKMENYLRHKQLCDVILVAGDRRIPAHRLVLSSVSDYFAAMF 202

  Fly   191 ----RKFIDKLPKLDQLGPDAGAERELFA---RVVAEE-----------VLQIPQLLRQLRSSLS 237
                |:...:..|::.:.|::......:|   |:..:|           :||:.|::......|.
Mouse   203 TNDVREARQEEIKMEGVEPNSLWSLIQYAYTGRLELKEDNIECLLSTACLLQLSQVVEACCKFLM 267

  Fly   238 KMEFFNEDTAFKAYLEVRYHPQARILCELMLTRISRV--------FLCIVGSPFFLYFTEHELTH 294
            |....:.....:::.:.:.       |    |.:.:|        |:.::.:..|:....:|:..
Mouse   268 KQLHPSNCLGIRSFADAQG-------C----TDLHKVAHNYTMEHFMEVIRNQEFVLLPANEIAK 321

  Fly   295 ILRNCYLSVNSEIEIFLSVVLWLEHNWLERGDCAERILAEVHFALMPTWYLCTLDRS 351
            :|.:..:::.:|..|..:::.|:.|:..:|.....|:||.:...|:...:|..::.:
Mouse   322 LLASDDMNIPNEETILNALLTWVRHDLEQRRKDLSRLLAYIRLPLLAPQFLADMENN 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14785	NP_569912.2	BACK	256..345	CDD:197943	16/96 (17%)
		DUF4734	359..450	CDD:434992
Klhl5	NP_780383.2	PHA03098	173..695	CDD:222983	34/217 (16%)
		KELCH repeat	457..500	CDD:276965
		KELCH repeat	504..548	CDD:276965
		KELCH repeat	551..594	CDD:276965
		KELCH repeat	598..648	CDD:276965
		KELCH repeat	651..694	CDD:276965