Protein Alignment CG14785 and KLHL28

DIOPT Version :10

• Sequence 1: NP_569912.2
• Gene: CG14785 / 31094
• FlyBaseID: FBgn0027795
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_001295041.1
• Gene: KLHL28 / 54813
• HGNCID: 19741
• Length: 585
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 56/294 - (19%)
• Similarity: 109/294 - (37%)
• Gaps: 71/294 - (24%)

  Fly    82 ASSTSAHAVKLLPIEGDPAKLKALTSRQQIASLLNHLGDGAEGDGEAKQIVMELLGSGVQPH--- 143
            |:.|..|:.:||  :|    |..|....::..::..:||...   .|.::|:    :.|.|:
Human    25 ANLTHLHSEQLL--QG----LNLLRQHHELCDIILRVGDVKI---HAHKVVL----ASVSPYFKA 76

  Fly   144 ----SAIERVSEQLLHVLREQTLMEAGIFVGNERYRFFKGVLQNYAKIYAARKFIDKLPKLDQLG 204
                :..|:.:.::.....::|.::|               :..||  |....||.: ..::.|.
Human    77 MFTGNLSEKENSEVEFQCIDETALQA---------------IVEYA--YTGTVFISQ-DTVESLL 123

  Fly   205 PDAGAERELFARVVAEEVLQIPQLLRQ----LRSSLSKMEFFNEDTAFKAY-LEVRYHPQARILC 264
            |             |..:|||..:|::    |.|.|............:.| ....|....:.:|
Human   124 P-------------AANLLQIKLVLKECCAFLESQLDPGNCIGISRFAETYGCRDLYLAATKYIC 175

  Fly   265 ELMLTRISRVFLCIVGSPFFLYFTEHELTHILRNCYLSVNSEIEIFLSVVLWLEHNWLERGDCAE 329
            :        .|..:..:..|...|..:|..|:.|..|:|.:|..:|.::..|::::..||.....
Human   176 Q--------NFEAVCQTEEFFELTHADLDEIVSNDCLNVATEETVFYALESWIKYDVQERQKYLA 232

  Fly   330 RILAEVHFALMPTWYLCTLDRSNR-------CNH 356
            ::|..|...|:...:|..|..:|.       |.|
Human   233 QLLNSVRLPLLSVKFLTRLYEANHLIRDDRTCKH 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14785	NP_569912.2	BACK	256..345	CDD:197943	18/88 (20%)
		DUF4734	359..450	CDD:434992
KLHL28	NP_001295041.1	PHA03098	49..567	CDD:222983	48/264 (18%)
		KELCH repeat	335..386	CDD:276965
		KELCH repeat	390..433	CDD:276965
		KELCH repeat	437..479	CDD:276965
		KELCH repeat	483..527	CDD:276965
		KELCH repeat	530..573	CDD:276965