Protein Alignment CG14785 and KLHL5

DIOPT Version :10

• Sequence 1: NP_569912.2
• Gene: CG14785 / 31094
• FlyBaseID: FBgn0027795
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: XP_047271704.1
• Gene: KLHL5 / 51088
• HGNCID: 6356
• Length: 804
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 49/319 - (15%)
• Similarity: 117/319 - (36%)
• Gaps: 80/319 - (25%)

  Fly    61 DRRPKPEPEKLESGAQGDAGSASSTSAHAVKLLPIEGDPAKLKALTSRQQIASLLNHLGDGAEGD 125
            |...:.|.|...|..:....|.:.:|.|.::  |...|           :....|||
Human   193 DGTSEEENESDSSSCRTSNSSQTLSSCHTME--PCTSD-----------EFFQALNH-------- 236

  Fly   126 GEAKQIVMELLGSGVQPHSAIERVSEQLLHVLREQTLMEAGIFVGNERYRFFKGVLQNYAKIYAA 190
                                .|:..:::.:.||.:.|.:..:..|:.|....:.||.:.:..:||
Human   237 --------------------AEQTFKKMENYLRHKQLCDVILVAGDRRIPAHRLVLSSVSDYFAA 281

  Fly   191 ------RKFIDKLPKLDQLGPDAGAERELFA---RVVAEE-----------VLQIPQLLRQLRSS 235
                  |:...:..|::.:.|::......:|   |:..:|           :||:.|::......
Human   282 MFTNDVREARQEEIKMEGVEPNSLWSLIQYAYTGRLELKEDNIECLLSTACLLQLSQVVEACCKF 346

  Fly   236 LSKMEFFNEDTAFKAYLEVRYHPQARILCELMLTRISRV--------FLCIVGSPFFLYFTEHEL 292
            |.|....:.....:::.:.:.       |    |.:.:|        |:.::.:..|:.....|:
Human   347 LMKQLHPSNCLGIRSFADAQG-------C----TDLHKVAHNYTMEHFMEVIRNQEFVLLPASEI 400

  Fly   293 THILRNCYLSVNSEIEIFLSVVLWLEHNWLERGDCAERILAEVHFALMPTWYLCTLDRS 351
            ..:|.:..:::.:|..|..:::.|:.|:..:|.....::||.:...|:...:|..::.:
Human   401 AKLLASDDMNIPNEETILNALLTWVRHDLEQRRKDLSKLLAYIRLPLLAPQFLADMENN 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14785	NP_569912.2	BACK	256..345	CDD:197943	15/96 (16%)
		DUF4734	359..450	CDD:434992
KLHL5	XP_047271704.1	PHA03098	254..775	CDD:222983	33/217 (15%)
		KELCH repeat	538..581	CDD:276965
		KELCH repeat	585..629	CDD:276965
		KELCH repeat	632..675	CDD:276965
		KELCH repeat	679..729	CDD:276965
		KELCH repeat	732..772	CDD:276965