DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG14785 and klhl24b

DIOPT Version :10

Sequence 1:NP_569912.2 Gene:CG14785 / 31094 FlyBaseID:FBgn0027795 Length:470 Species:Drosophila melanogaster
Sequence 2:NP_956734.1 Gene:klhl24b / 393412 ZFINID:ZDB-GENE-040426-1185 Length:398 Species:Danio rerio


Alignment Length:356 Identity:62/356 - (17%)
Similarity:127/356 - (35%) Gaps:111/356 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   127 EAKQIVMELLGSGVQPHSAIERVSEQLLHVLREQTLMEAGIFVGNERYRFFKGVLQNYAKIY-AA 190
            |::::::|:  :|::    .|.:...|.:|...:    |.|...|.::.|....|...:.:. |.
Zfish   101 ESREMLVEI--NGIR----AEAMDTFLQYVYTGR----ARITTDNVQFLFETSSLFQISTLRDAC 155

  Fly   191 RKFIDKLPKLDQLGP--DAGAERELFARVVAEEVLQIPQLLRQLRSSLSKMEFFNEDTAFKAYLE 253
            .||::     |||.|  ..|.:|  ||     :...:.||..:.||           .|.:::.:
Zfish   156 AKFLE-----DQLDPCNCLGIQR--FA-----DAHSLKQLASRCRS-----------YALQSFAD 197

  Fly   254 VRYHPQARILCELMLTRISRVFLCIVGSPFFLYFTEHELTHILRNCYLSVNSEIEIFLSVVLWLE 318
            |..|.:                        ||...:.||...:.:..:.:..|..:|.:|:.|:.
Zfish   198 VAQHEE------------------------FLDLRKEELEEYIASDEMVIGKEETVFEAVMRWVY 238

  Fly   319 HNWLERGDCAERILAEVHFALM-PTWYLCTLD------RSNRCN---HFARVIHSPGVQRLIAAG 373
            ::...|....:.:|..|...|: |.:::.|::      .:..|.   |.||..|..|        
Zfish   239 YDVDHRRIMLKDLLNHVRLPLLHPNYFVQTVEGDQLIQNAPECYQLLHEARRYHVLG-------- 295

  Fly   374 LEDAITLKSKPRFSGAALHRQRKHQEERLLVRDWIVDTECSHHHKSHCEQ---FVYPTYDAFKEY 435
             .:.::.:::||       |.....|..::|              ..||:   |..|..:.:...
Zfish   296 -NEMMSPRTRPR-------RSTGFSEVIVVV--------------GGCERMGGFNLPYTECYDPV 338

  Fly   436 LARIICCAPNCWRTFRPAQEVYRRDFRCCSL 466
            ...        |::.....|..:.::..|:|
Zfish   339 TGE--------WKSLAKLPEFTKSEYAVCAL 361

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14785NP_569912.2 BACK 256..345 CDD:197943 14/89 (16%)
DUF4734 359..450 CDD:434992 13/93 (14%)
klhl24bNP_956734.1 BTB_POZ_KLHL24_KRIP6 48..168 CDD:349562 18/81 (22%)
BACK 163..276 CDD:475122 27/154 (18%)
NanM 315..>385 CDD:442289 9/69 (13%)

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