Protein Alignment CG14785 and Klhl41

DIOPT Version :10

• Sequence 1: NP_569912.2
• Gene: CG14785 / 31094
• FlyBaseID: FBgn0027795
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_001074556.1
• Gene: Klhl41 / 228003
• MGIID: 2683854
• Length: 606
• Species: Mus musculus
• Alignment Length: 280
• Identity: 57/280 - (20%)
• Similarity: 100/280 - (35%)
• Gaps: 83/280 - (29%)

  Fly   149 VSEQLLHVLREQTLMEAGIFVGNERY---RFFKGVLQNYAKIYAARKFIDKLPK---LDQLGP-- 205
            :.:.|..:|.|:..::..:..|::.:   |........|.:.|...:..::..|   ||.:.|
Mouse    19 LQDGLKDLLEEKKFIDCTLKAGDKSFPCHRLILSACSPYFREYFLSEIEEEKKKEVALDNVDPAI 83

  Fly   206 ---------------DAGAERELFARVVAEEVLQIPQLLRQLRSSLSKMEFFNEDTAFKAYLEVR 255
                           :.|..:::||   .....|||.:.                |...:||:.|
Mouse    84 LDLIIKYLYSASIDLNDGNVQDIFA---LSSRFQIPSVF----------------TVCVSYLQKR 129

  Fly   256 YHP---QARILCELML----------TRISRVFLCIVGSPFFLYFTEHELTHILRNCYLSVNSEI 307
            ..|   .|.:...|:|          ..:|..|:.|.....|:..:..||..::.|..|:|..|.
Mouse   130 LAPGNCLAILRLGLLLDCPRLAISAREFVSDRFVQICKEEDFMQLSPQELISVISNDSLNVEKEE 194

  Fly   308 EIFLSVVLWLE-------HNWLERGDCAE-RILAEVHFALMPTWYLCTLDRSNRCNHFAR--VIH 362
            .:|.:|:.|:.       .|..|..||.. |::||.:|.                :|..:  :|.
Mouse   195 VVFEAVMKWVRTDKENRAKNLSEVFDCIRFRLMAEKYFK----------------DHVEKDDIIK 243

  Fly   363 S-PGVQRLIAAGLEDAITLK 381
            | |.||:.|.. |:||...|
Mouse   244 SNPEVQKKIKV-LKDAFAGK 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14785	NP_569912.2	BACK	256..345	CDD:197943	25/109 (23%)
		DUF4734	359..450	CDD:434992	10/26 (38%)
Klhl41	NP_001074556.1	BTB_POZ_KLHL41_KBTBD10	6..135	CDD:349650	22/134 (16%)
		PHA03098	39..578	CDD:222983	54/260 (21%)
		KELCH repeat	335..384	CDD:276965
		Kelch 1	346..398
		KELCH repeat	388..433	CDD:276965
		Kelch 2	399..447
		KELCH repeat	437..482	CDD:276965
		Kelch 3	448..495
		KELCH repeat	485..530	CDD:276965
		Kelch 4	497..542
		Kelch 5	544..599