DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssx and hnrnpa1a

DIOPT Version :9

Sequence 1:	NP_569908.1	Gene:	ssx / 31086	FlyBaseID:	FBgn0024987	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_021335234.1	Gene:	hnrnpa1a / 393467	ZFINID:	ZDB-GENE-040426-1546	Length:	445	Species:	Danio rerio

Alignment Length:	395	Identity:	90/395 - (22%)
Similarity:	140/395 - (35%)	Gaps:	109/395 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 SAGQQQQMQQVDRTSATNLIINYLPQDMTDRELYNLFSGCGPINTC------------------- 122
            :|..::|....:......|.|..|..:.||..|...|...|.:..|
Zfish    22 TAMSKEQQTPREPEQLRKLFIGGLSFETTDESLRAHFEQWGTLTDCVVSPSAAIHMLMYEREEHL 86

  Fly   123 ---------KIMRDFKTGYSFGYGFVDYKTESDSEDAI----QKLNGFYVRNKRL--KVSYARPG 172
                     ::|||..|..|.|:|||.|.:..:.:.|:    .|::|..|..||.  :...::||
Zfish    87 KVAGFLYCSQVMRDPNTKRSRGFGFVTYSSVGEVDAAMDARPHKVDGRAVEPKRAVSREDSSKPG 151

  Fly   173 GQS-IKDTNLYVINLSRNINDDMLDRIFSPYGLIVQRNILRDKLTGRPRGVAFVRYNKREEAQEA 236
            ..| :|  .::|..:..:.:::.|...|..:|.|.:.||:.:|.:.:.||.||:.::..:.....
Zfish   152 AHSTVK--KMFVGGIKEDTDEEHLREYFGQFGKIDEVNIMTEKNSDKRRGFAFITFDDHDAVDRI 214

  Fly   237 IKALNNTVPEGGSQPIWVRLAEEH--------------GKAKAAQFMAQIGGGNGGGGGGPPHMG 287
            :....:|| .|.:..:...|:.|.              |.........:.|||.||||.|..:.|
Zfish   215 VIQKYHTV-NGHNCEVRKALSREEMNRVSMNSRGGRGGGGGSGGGNFGRGGGGGGGGGYGGGYGG 278

  Fly   288 PGGPMHPPHHHNNHHHNNHHNPHMPPHHHQPQHPHQHPQHHPQLHHMQHHHPNNHNNNHPNNHHH 352
            .||......:.....:|.:..                                           .
Zfish   279 GGGRGGGGGYGGGDGYNGYGG-------------------------------------------G 300

  Fly   353 NNNNNNHHNMGGPHPHHMQQMHPMGMNMGMGVNMGMGMGMGMPIHGGGGGGGG-------GGGGG 410
            |..:.:....||..|::       |.|.|.|...|.|.|.|....|||.||||       |||||
Zfish   301 NGISTDKSGYGGGGPNY-------GGNRGYGSGGGGGGGGGYGNQGGGYGGGGYDNYNNNGGGGG 358

  Fly   411 GGGNF 415
            |||||
Zfish   359 GGGNF 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssx	NP_569908.1	RRM_SF	93..173	CDD:302621	26/113 (23%)
ssx	NP_569908.1	RRM_SF	179..257	CDD:302621	15/77 (19%)
hnrnpa1a	XP_021335234.1	RRM_SF	36..144	CDD:327398	25/107 (23%)
		RRM_SF	157..233	CDD:327398	16/78 (21%)
		HnRNPA1	376..>392	CDD:314495
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920