DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssx and RBMY1E

DIOPT Version :9

Sequence 1:	NP_569908.1	Gene:	ssx / 31086	FlyBaseID:	FBgn0024987	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001006118.2	Gene:	RBMY1E / 378950	HGNCID:	23916	Length:	496	Species:	Homo sapiens

Alignment Length:	303	Identity:	59/303 - (19%)
Similarity:	107/303 - (35%)	Gaps:	90/303 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 LIINYLPQDMTDRELYNLFSGCGPINTCKIMRDFKTGYSFGYGFVDYKTESDSEDAIQKLNGFYV 159
            |.|..|.::..::.|..:|...|||:...:::| :|..|.|:.|:.::..:|:::|.:.:||..:
Human    10 LFIGGLNRETNEKMLKAVFGKHGPISEVLLIKD-RTSKSRGFAFITFENPADAKNAAKDMNGKSL 73

  Fly   160 RNKRLKVSYAR-----PGGQSIKDTNLYVINLSRNINDDMLDRIFSPYGLIVQRNILRDKLTGRP 219
            ..|.:||..|:     .||:.....:      |||         .||.|.:......|    |..
Human    74 HGKAIKVEQAKKPSFQSGGRRRPPAS------SRN---------RSPSGSLRSARGSR----GGT 119

  Fly   220 RGVAFVRYNKREEAQEAIKALNNTVPEGGSQPIWVRLAEEHGKAKAAQFMAQIGGGNGGGGGGPP 284
            ||              .:.:....:.:||..|. ::::...|       :..:..|.....||||
Human   120 RG--------------WLPSQEGHLDDGGYTPD-LKMSYSRG-------LIPVKRGPSSRSGGPP 162

  Fly   285 --------------HMGPGGPMH--------PPHH-----HNNHHHNNHHNPHMPPHHHQPQHPH 322
                          .||..|||.        ||..     ..|...:..|:.:.
Human   163 PKKSAPSAVARSNSWMGSQGPMSQRRENYGVPPRRATISSWRNDRMSTRHDGYA----------- 216

  Fly   323 QHPQHHPQLHHMQHHHPNN-----HNNNHPNNHHHNNNNNNHH 360
            .:..:||.....:.:.|.:     .:|.|.|...|::....:|
Human   217 TNDGNHPSCQETRDYAPPSRGYAYRDNGHSNRDEHSSRGYRNH 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssx	NP_569908.1	RRM_SF	93..173	CDD:302621	21/82 (26%)
ssx	NP_569908.1	RRM_SF	179..257	CDD:302621	13/77 (17%)
RBMY1E	NP_001006118.2	RRM	<1..189	CDD:223796	47/220 (21%)
		RRM_RBMX_like	7..85	CDD:240828	21/75 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	67..348		44/245 (18%)
		RBM1CTR	174..218	CDD:285341	9/54 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	453..496
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910