DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ssx and Hnrnpa3

DIOPT Version :9

Sequence 1:	NP_569908.1	Gene:	ssx / 31086	FlyBaseID:	FBgn0024987	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_001104764.1	Gene:	Hnrnpa3 / 362152	RGDID:	727807	Length:	379	Species:	Rattus norvegicus

Alignment Length:	390	Identity:	91/390 - (23%)
Similarity:	145/390 - (37%)	Gaps:	101/390 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 GDGQEHSGDEEQHHSQDNEGNDNSAGQQQQMQQVDRTSATNLIINYLPQDMTDRELYNLFSGCGP 118
            |..|..||...:...:  ||:|....:|.:          .|.|..|..:.||..|...|...|.
  Rat     8 GRPQPDSGRRRRRRGE--EGHDPKEPEQLR----------KLFIGGLSFETTDDSLREHFEKWGT 60

  Fly   119 INTCKIMRDFKTGYSFGYGFVDYKTESDSEDAI----QKLNGFYVRNKRL--KVSYARPGGQ-SI 176
            :..|.:|||.:|..|.|:|||.|....:.:.|:    .|::|..|..||.  :....:||.. ::
  Rat    61 LTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTV 125

  Fly   177 KDTNLYVINLSRNINDDMLDRIFSPYGLIVQRNILRDKLTGRPRGVAFVRYNKREEAQEAIKALN 241
            |  .::|..:..:..:..|...|..||.|....::.|:.:|:.||.|||.::..:...:.:....
  Rat   126 K--KIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKY 188

  Fly   242 NTVPEGGSQPIWVRLAEEHGKAKAAQ---------FMAQIGGGNGGGGGGPPHMGPGGPMHPPHH 297
            :|: .|.:..:...|:::..::..:|         ||.:  |||.|||||  :.|.||
  Rat   189 HTI-NGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGR--GGNFGGGGG--NFGRGG------- 241

  Fly   298 HNNHHHNNHHNPHMPPHHHQPQHPHQHPQHHPQLHHMQHHHPNNHNNNHPNNHHHNNNNNNHHNM 362
              |......:.                                  .....:...:...:..::..
  Rat   242 --NFGGRGGYG----------------------------------GGGGGSRGSYGGGDGGYNGF 270

  Fly   363 GGPHPHHMQQMHPMGMNMGMGVNMGM--GMGMGMPIHGGGGGGGGGGGGG----------GGGNF 415
            ||.           |.|.|.|.....  |.|.|.|.:|..|||.||||||          ||||:
  Rat   271 GGD-----------GGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDGYNEGGNFGGGNY 324

Fly 416 415
Rat 325 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssx	NP_569908.1	RRM_SF	93..173	CDD:302621	26/85 (31%)
ssx	NP_569908.1	RRM_SF	179..257	CDD:302621	15/77 (19%)
Hnrnpa3	NP_001104764.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35		8/28 (29%)
		RRM1_hnRNPA_like	36..113	CDD:409992	25/76 (33%)
		RRM2_hnRNPA3	126..205	CDD:409996	17/81 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	204..225		2/20 (10%)
		HnRNPA1	332..>348	CDD:402981
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	335..379
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010