DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ssx and hnrnpa3

DIOPT Version :9

Sequence 1:	NP_569908.1	Gene:	ssx / 31086	FlyBaseID:	FBgn0024987	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	XP_031748359.1	Gene:	hnrnpa3 / 100144993	XenbaseID:	XB-GENE-5878765	Length:	385	Species:	Xenopus tropicalis

Alignment Length:	372	Identity:	93/372 - (25%)
Similarity:	145/372 - (38%)	Gaps:	93/372 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 SQDNEGNDNSAGQQQQMQQVDRTSATNLIINYLPQDMTDRELYNLFSGCGPINTCKIMRDFKTGY 132
            |.|::|::....:|.:          .|.|..|..:.||..|...|...|.:..|.:|||.:|..
Frog    78 STDDQGHEPKEPEQLR----------KLFIGGLSFETTDDSLREHFEQWGKLTDCVVMRDPQTKR 132

  Fly   133 SFGYGFVDYKTESDSEDAI----QKLNGFYVRNKRL--KVSYARPGGQ-SIKDTNLYVINLSRNI 190
            |.|:|||.|....:.:.|:    .|::|..|..||.  :...||||.. ::|  .::|..:..:.
Frog   133 SRGFGFVTYSCVEEVDAAMSARPHKVDGRVVEPKRAVSREDSARPGAHLTVK--KIFVGGIKEDT 195

  Fly   191 NDDMLDRIFSPYGLIVQRNILRDKLTGRPRGVAFVRYNKREEAQEAIKALNNTVPEGGSQPIWVR 255
            .:..|...|..||.|....::.|:.:|:.||.|||.::..:...:.:....:|: .|.:..:...
Frog   196 EEYHLRDYFQSYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTI-NGHNCEVKKA 259

  Fly   256 LAEEHGKAKAAQFMAQIGGGNGGGG---GGPP------------HMGPGGPMHPPHHHNNHHHNN 305
            |:::..:..:||.....|||.|.||   ||.|            ..|.||
Frog   260 LSKQEMQTASAQRGGNYGGGPGYGGRGYGGSPGYGNQGGGYGGGGSGGGG--------------- 309

  Fly   306 HHNPHMPPHHHQPQHPHQHPQHHPQLHHMQHHHPNNHNNNHPNNHHHNNNNNNHHNMGGPHPHHM 370
                                              ..::..:...:....|.|:..|.||     .
Frog   310 ----------------------------------GGYDGYNEGGNFGGGNYNDFGNYGG-----Q 335

  Fly   371 QQMH--PMGMNMGMGVNMGMGMGMGMPIHGGGGGGGGGGGGGGGGNF 415
            ||.:  ||......|.:.| |.|.| |..||.|.|||||||||||::
Frog   336 QQSNYGPMKGGSFSGRSSG-GSGSG-PYGGGYGSGGGGGGGGGGGSY 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ssx	NP_569908.1	RRM_SF	93..173	CDD:302621	28/85 (33%)
ssx	NP_569908.1	RRM_SF	179..257	CDD:302621	15/77 (19%)
hnrnpa3	XP_031748359.1	RRM1_hnRNPA_like	94..171	CDD:409992	25/76 (33%)
		RRM2_hnRNPA3	184..263	CDD:409996	17/81 (21%)
		HnRNPA1	328..>344	CDD:402981	6/20 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1202220at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920