Protein Alignment png and Nek5

DIOPT Version :10

• Sequence 1: NP_477492.1
• Gene: png / 31084
• FlyBaseID: FBgn0000826
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: XP_008769592.1
• Gene: Nek5 / 685440
• RGDID: 1593817
• Length: 677
• Species: Rattus norvegicus
• Alignment Length: 257
• Identity: 86/257 - (33%)
• Similarity: 137/257 - (53%)
• Gaps: 40/257 - (15%)

  Fly     7 KLRAVRVLGQGTFGRVFL-------CHQNEVRGQPERKVCVKRIIVRNPKTELGLIKEEVYIISQ 64
            |...::::|:||||:|:|       ||            ||.:.|....:.|..  |.||.::::
  Rat     3 KFDLIKIIGEGTFGKVYLAKDKSESCH------------CVIKEISLTKEKEAS--KNEVTLLAK 53

  Fly    65 LRHPHIVEFLRSFSHAGTVNIVMEYVPNGTLRDVIQQLPSGTGGV--NQERLMGYFRDMVVGLEY 127
            ::|.:||.|..||.....:.|||||...|.|.:.||:    ..||  ::::::.:|..:.:||::
  Rat    54 MKHSNIVTFFSSFQENSRLFIVMEYCDGGDLMERIQR----QRGVLFSEDQILCWFVQISLGLKH 114

  Fly   128 LHIRCVIHRDIKPENMLLDANDRV-KIADFGIANVHAPSTQL-QAGMGTPMYMAPEAMSSQGKVD 190
            :|.:.|:|||||.:|:.|..|..| |:.|||.|.....|.:| |...|||.|::||...:: ..:
  Rat   115 IHDKKVLHRDIKSQNIFLSKNGMVAKLGDFGTARTLNNSMELAQTCAGTPYYLSPEICQNR-PYN 178

  Fly   191 FKSDVWSLGLVLYELCLGRSPFAAFLDKNATPALLHTVVQALVRP-----RLDCQ-LIRRLY 246
            .|:|:||||.||||||..:.||    :.:....|:..:.|..|.|     .||.| ||.:|:
  Rat   179 NKTDIWSLGCVLYELCTLKHPF----ESDNLHHLVLKICQGRVAPISPHFSLDLQSLIPQLF 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
png	NP_477492.1	S_TKc	11..271	CDD:214567	85/253 (34%)
Nek5	XP_008769592.1	Protein Kinases, catalytic domain	3..255	CDD:473864	86/257 (33%)