| Sequence 1: | NP_477492.1 | Gene: | png / 31084 | FlyBaseID: | FBgn0000826 | Length: | 291 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002488.1 | Gene: | NEK2 / 4751 | HGNCID: | 7745 | Length: | 445 | Species: | Homo sapiens |
| Alignment Length: | 215 | Identity: | 73/215 - (33%) |
|---|---|---|---|
| Similarity: | 114/215 - (53%) | Gaps: | 16/215 - (7%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 14 LGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRNPKTEL--GLIKEEVYIISQLRHPHIVEFL-R 75
Fly 76 SFSHAG-TVNIVMEYVPNGTLRDVIQQLPSGTGGVNQERLMGYFRDMVVGLEYLHIR-----CVI 134
Fly 135 HRDIKPENMLLDANDRVKIADFGIANVHAPSTQL-QAGMGTPMYMAPEAMSSQGKVDFKSDVWSL 198
Fly 199 GLVLYELCLGRSPFAAFLDK 218 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| png | NP_477492.1 | S_TKc | 11..271 | CDD:214567 | 73/215 (34%) |
| NEK2 | NP_002488.1 | STKc_Nek2 | 7..271 | CDD:270857 | 73/215 (34%) |
| Interaction with PCNT. /evidence=ECO:0000269|PubMed:20599736 | 264..445 | ||||
| Interaction with CEP85. /evidence=ECO:0000269|PubMed:26220856 | 301..445 | ||||
| Leucine-zipper | 306..334 | ||||
| Necessary for interaction with MAD1L1. /evidence=ECO:0000269|PubMed:14978040 | 329..445 | ||||
| Required for microtubule binding and for localization to the centrosomes | 333..370 | ||||
| Interaction with SAV1 and STK3/MST2. /evidence=ECO:0000269|PubMed:21076410 | 403..439 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||