DRSC/TRiP Functional Genomics Resources

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Protein Alignment png and nek8

DIOPT Version :10

Sequence 1:NP_477492.1 Gene:png / 31084 FlyBaseID:FBgn0000826 Length:291 Species:Drosophila melanogaster
Sequence 2:XP_012812229.1 Gene:nek8 / 448753 XenbaseID:XB-GENE-990378 Length:698 Species:Xenopus tropicalis


Alignment Length:287 Identity:92/287 - (32%)
Similarity:154/287 - (53%) Gaps:35/287 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 KLRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRN-PKTELGLIKEEVYIISQLRHPHI 70
            |.:.:||:|:|.||.|.||    :|...::.|.:|:|.|.. .|.|....:.|..::..|.||:|
 Frog     3 KYKKIRVVGRGAFGIVHLC----LRKADQKLVIIKQIPVEQMTKDERLAAQNECQVLKLLSHPNI 63

  Fly    71 VEFLRSFSHAGTVNIVMEYVPNGTLRDVIQQLPSGTGGVNQERLMGYFRDMVVGLEYLHIRCVIH 135
            :|:..:|.....:.|||||.|.|||.:.||:..:..  ::::.::.:|..:::.|.::|.:.::|
 Frog    64 IEYYENFLEDKALMIVMEYAPGGTLAEYIQKRCNSL--LDEDTILHFFVQILLALHHVHTKLILH 126

  Fly   136 RDIKPENMLLDANDR-VKIADFGIANVHAPSTQLQAGMGTPMYMAPEAMSSQGK-VDFKSDVWSL 198
            ||:|.:|:|||.:.. |||.||||:.:.:..::....:|||.|::||.  .:|| .:.|||:|:|
 Frog   127 RDLKTQNILLDKHQMIVKIGDFGISKILSSKSKAYTVVGTPCYISPEL--CEGKPYNQKSDIWAL 189

  Fly   199 GLVLYEL-CLGRSPFAAFLDKNATPALLHTVVQALVRPRLDCQLIRRLYDPVWAQVCELMVVYEQ 262
            |.||||| .|.|:..||.|     |||:..::.....|      |...|.|....:...|:..:.
 Frog   190 GCVLYELTSLKRAFEAANL-----PALVLKIMSGTFAP------ISDRYSPELRHLILSMLNLDP 243

  Fly   263 ERR----------ICLPDIFHL--DAG 277
            .:|          ||:|.:.:|  |.|
 Frog   244 SKRPQLNEIMAHPICIPALLNLYSDIG 270

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pngNP_477492.1 S_TKc 11..271 CDD:214567 88/273 (32%)
nek8XP_012812229.1 STKc_Nek8 3..258 CDD:270859 86/273 (32%)
ATS1 343..685 CDD:444065
Blue background indicates that the domain is not in the aligned region.

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