Protein Alignment png and NEK5

DIOPT Version :10

• Sequence 1: NP_477492.1
• Gene: png / 31084
• FlyBaseID: FBgn0000826
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: XP_047286243.1
• Gene: NEK5 / 341676
• HGNCID: 7748
• Length: 904
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 82/234 - (35%)
• Similarity: 137/234 - (58%)
• Gaps: 18/234 - (7%)

  Fly     7 KLRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRII--VRNPKTELGLIKEEVYIISQLRHPH 69
            |...::.:|||.||:.:|     .:|:.:.|.||.:.|  .:.|..|....|:||.::.:::||:
Human    75 KYDVIKAIGQGAFGKAYL-----AKGKSDSKHCVIKEINFEKMPIQEKEASKKEVILLEKMKHPN 134

  Fly    70 IVEFLRSFSHAGTVNIVMEYVPNGTLRDVIQQLPSGTGGV-NQERLMGYFRDMVVGLEYLHIRCV 133
            ||.|..||...|.:.|||||...|   |:::::....|.: ::::::|:|..:.:||:::|.|.:
Human   135 IVAFFNSFQENGRLFIVMEYCDGG---DLMKRINRQRGVLFSEDQILGWFVQISLGLKHIHDRKI 196

  Fly   134 IHRDIKPENMLLDANDRV-KIADFGIANVHAPSTQL-QAGMGTPMYMAPEAMSSQGKVDFKSDVW 196
            :|||||.:|:.|..|..| |:.|||||.|...|.:| :..:|||.|::||...:: ..:.|:|:|
Human   197 LHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELARTCIGTPYYLSPEICQNK-PYNNKTDIW 260

  Fly   197 SLGLVLYELCLGRSPFAAFLDKNATPALLHTVVQALVRP 235
            |||.||||||..:.||    :.|....|:..:.||...|
Human   261 SLGCVLYELCTLKHPF----EGNNLQQLVLKICQAHFAP 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
png	NP_477492.1	S_TKc	11..271	CDD:214567	81/230 (35%)
NEK5	XP_047286243.1	STKc_Nek5	75..331	CDD:173765	82/234 (35%)