Protein Alignment png and Nek3

DIOPT Version :10

• Sequence 1: NP_477492.1
• Gene: png / 31084
• FlyBaseID: FBgn0000826
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: XP_006253421.1
• Gene: Nek3 / 306576
• RGDID: 1307419
• Length: 471
• Species: Rattus norvegicus
• Alignment Length: 252
• Identity: 80/252 - (31%)
• Similarity: 137/252 - (54%)
• Gaps: 28/252 - (11%)

  Fly    11 VRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRNPKTELGLIKEEVYIISQLRHPHIVEFLR 75
            :||:|.|:||.|.|..:.    ...:...:|.|.:....:::...::|..::::::||:||.|..
  Rat     7 LRVIGHGSFGSVLLATEK----SSNQTFAMKEIRLLKSFSDVQNCRKEAVLLAKMKHPNIVAFKE 67

  Fly    76 SFSHAGTVNIVMEYVPNGTLRDVIQQLPSGTGGV-NQERLMGYFRDMVVGLEYLHIRCVIHRDIK 139
            ||...|.:.|||||...|   |:.|::....|.: .::.::.:|..:.:|:.::|.|.|:|||||
  Rat    68 SFEAEGHLYIVMEYCDGG---DLTQRIKQQKGKLFPEDTVLNWFIQICLGVNHIHKRRVLHRDIK 129

  Fly   140 PENMLLDANDRVKIADFGIAN-VHAPSTQLQAGMGTPMYMAPEAMSSQGKVDFKSDVWSLGLVLY 203
            .:|:.|..:.:||:.|||.|. :.:|....:..:|||.|:.||...:. ..:.|||:||||.:||
  Rat   130 SKNVFLTHDGKVKLGDFGSARLLSSPMAFARTYVGTPYYVPPEIWENL-PYNNKSDIWSLGCILY 193

  Fly   204 ELCLGRSPFAAFLDKN-----------ATPALLHTVVQALVRPRLDCQLIRRLYDPV 249
            |||..:.||.|...||           ..|||..:.:|.||:     |:::|  :||
  Rat   194 ELCALKHPFQANSWKNLILKICQGPIHPLPALYSSKLQCLVK-----QMLKR--NPV 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
png	NP_477492.1	S_TKc	11..271	CDD:214567	80/252 (32%)
Nek3	XP_006253421.1	Protein Kinases, catalytic domain	3..257	CDD:473864	80/252 (32%)