Protein Alignment png and NEK8

DIOPT Version :10

• Sequence 1: NP_477492.1
• Gene: png / 31084
• FlyBaseID: FBgn0000826
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: NP_835464.1
• Gene: NEK8 / 284086
• HGNCID: 13387
• Length: 692
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 89/274 - (32%)
• Similarity: 147/274 - (53%)
• Gaps: 26/274 - (9%)

  Fly     7 KLRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRN-PKTELGLIKEEVYIISQLRHPHI 70
            |...:||:|:|.||.|.||    :|...::.|.:|:|.|.. .|.|....:.|..::..|.||::
Human     3 KYERIRVVGRGAFGIVHLC----LRKADQKLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNV 63

  Fly    71 VEFLRSFSHAGTVNIVMEYVPNGTLRDVIQQLPSGTGGVNQERLMGYFRDMVVGLEYLHIRCVIH 135
            :|:..:|.....:.|.|||.|.|||.:.||:..:..  :.:|.::.:|..:::.|.::|...::|
Human    64 IEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSL--LEEETILHFFVQILLALHHVHTHLILH 126

  Fly   136 RDIKPENMLLDANDR-VKIADFGIANVHAPSTQLQAGMGTPMYMAPEAMSSQGK-VDFKSDVWSL 198
            ||:|.:|:|||.:.. |||.||||:.:.:..::....:|||.|::||.  .:|| .:.|||:|:|
Human   127 RDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPEL--CEGKPYNQKSDIWAL 189

  Fly   199 GLVLYELC-LGRSPFAAFLDKNATPALLHTVVQALVRPRLDCQLIRRLYDPVWAQVCELMVVYEQ 262
            |.|||||. |.|:..||.|     |||:..::.....|      |...|.|...|:...::..|.
Human   190 GCVLYELASLKRAFEAANL-----PALVLKIMSGTFAP------ISDRYSPELRQLVLSLLSLEP 243

  Fly   263 ERRICLPDIFHLDA 276
            .:|   |.:.|:.|
Human   244 AQR---PPLSHIMA 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
png	NP_477492.1	S_TKc	11..271	CDD:214567	86/263 (33%)
NEK8	NP_835464.1	STKc_Nek8	3..258	CDD:270859	89/274 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	277..301
		RCC1 1	312..350
		ATS1	313..647	CDD:444065
		RCC1 2	410..461
		RCC1 3	462..513
		RCC1 4	580..631
		RCC1 5	632..684
		RCC1	633..673	CDD:395335