DRSC/TRiP Functional Genomics Resources

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Protein Alignment png and nekl-1

DIOPT Version :10

Sequence 1:NP_477492.1 Gene:png / 31084 FlyBaseID:FBgn0000826 Length:291 Species:Drosophila melanogaster
Sequence 2:NP_001293320.1 Gene:nekl-1 / 189769 WormBaseID:WBGene00021461 Length:983 Species:Caenorhabditis elegans


Alignment Length:278 Identity:83/278 - (29%)
Similarity:135/278 - (48%) Gaps:44/278 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 SKLRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRN-PKTELGLIKEEVYIISQLRHPH 69
            ::...:|.:|:|.||...|..:.|    ....|.:|.|.:.: ..::..|...||.::|::.||:
 Worm   169 NRYERIRTVGKGAFGSAVLYRRRE----DSSLVIIKEINMYDLDSSQRRLALNEVSLLSRIEHPN 229

  Fly    70 IVEFLRSFSHAGTVNIVMEYVPNGTLRDVIQQLPSGTGGVNQERLMGYFRDMVV----GLEYLHI 130
            |:.:..||...|.:.|.|||...|||    .|:.|.|..:..|..:|   ||::    .:.|||.
 Worm   230 IIAYYDSFEEEGVLMIEMEYADGGTL----AQMLSRTQNLLDEEQIG---DMMIQMCSAVAYLHE 287

  Fly   131 RCVIHRDIKPENMLLDANDRVKIADFGIANVHAPSTQLQAG---MGTPMYMAPEAMSSQGKVDFK 192
            ..|:|||:|..|:.|..:..|||.||||:.:....|..|..   :|||.|::|| |.|....:.|
 Worm   288 NSVLHRDLKTANVFLTRDSFVKIGDFGISKIMGTETLAQGAKTVVGTPYYISPE-MCSGVSYNEK 351

  Fly   193 SDVWSLGLVLYELCLGRSPFAAFLDKNATPALLHTVVQALVRPRLDCQLIRRLYDPVWAQVCELM 257
            ||:|:||.:|||:|..:..|    :.:..|||::::        :.|     .|.||...     
 Worm   352 SDMWALGCILYEMCCLKKAF----EGDNLPALVNSI--------MTC-----AYTPVKGP----- 394

  Fly   258 VVYEQERRICLPDIFHLD 275
              |..|.::.:.::..||
 Worm   395 --YSAEMKMVIRELLQLD 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pngNP_477492.1 S_TKc 11..271 CDD:214567 81/267 (30%)
nekl-1NP_001293320.1 STKc_Nek 170..423 CDD:270855 83/277 (30%)
ATS1 471..>765 CDD:444065
Blue background indicates that the domain is not in the aligned region.

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