Protein Alignment png and nekl-4

DIOPT Version :10

• Sequence 1: NP_477492.1
• Gene: png / 31084
• FlyBaseID: FBgn0000826
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: NP_498178.3
• Gene: nekl-4 / 175760
• WormBaseID: WBGene00017033
• Length: 981
• Species: Caenorhabditis elegans
• Alignment Length: 308
• Identity: 84/308 - (27%)
• Similarity: 141/308 - (45%)
• Gaps: 56/308 - (18%)

  Fly     2 ELGDSKLRAVRVLGQGTFGRVFLCHQNEVRGQ-----PERKVCVKRIIVRN------PKTELGLI 55
            |:|:.:|  :..||.|.||.|:...:   :.|     |.:.:.:|.|.:.|      .|:...:|
 Worm   449 EVGEYEL--LDQLGAGAFGCVYTVRK---KAQSHSENPAKLLALKEIFMTNLNDRESDKSFGDMI 508

  Fly    56 KEEVYIISQLRHPHIVEFLRSFSHAGTVNIVMEYVPNGTLRDVIQQLPSGTGGVNQERLMGYFRD 120
            .|...|..|||||:||.:.|.|.....:.|||:.:...:|||:|..:....|...::::......
 Worm   509 SEVKIIKQQLRHPNIVRYRRIFVENHRLYIVMDLIQGCSLRDLIITMKEKKGNFEEKKIWAMVVQ 573

  Fly   121 MVVGLEYLH-IRCVIHRDIKPENMLLDANDRVKIADFGIANVHAPSTQLQAGMGTPMYMAPEAMS 184
            |::.|.||| .:.::|||:||.|:::..::||.|.|||:|....|. .|::..||.:|..||.:.
 Worm   574 MMLALRYLHKEKQIVHRDLKPNNIMMTTDERVVITDFGLAKQKGPE-YLKSAAGTIIYSCPEIVQ 637

  Fly   185 S--QGKVDFKSDVWSLGLVLYELCLGRSPFAAFLDKNATPALLHTVVQALVRPRLDCQLIRRLYD 247
            :  .|:   |:|:||.|..:||:|                 .|..|..:.....|..|::...||
 Worm   638 NLPYGE---KADIWSFGCCIYEMC-----------------QLQPVFHSTNMLTLAMQIVEAKYD 682

  Fly   248 P---VWAQVCELMVVYEQERRICL-------PDIFHLDAGMTVTLYKH 285
            |   :|:.....::.      .||       |||..:.....|.|.::
 Worm   683 PLNEMWSDDLRFLIT------SCLAPDPSARPDILKVSGMCGVRLLEY 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
png	NP_477492.1	S_TKc	11..271	CDD:214567	77/283 (27%)
nekl-4	NP_498178.3	Protein Kinases, catalytic domain	452..719	CDD:473864	80/298 (27%)