DRSC/TRiP Functional Genomics Resources

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Protein Alignment png and Nek8

DIOPT Version :10

Sequence 1:NP_477492.1 Gene:png / 31084 FlyBaseID:FBgn0000826 Length:291 Species:Drosophila melanogaster
Sequence 2:XP_006532246.1 Gene:Nek8 / 140859 MGIID:1890646 Length:702 Species:Mus musculus


Alignment Length:274 Identity:89/274 - (32%)
Similarity:147/274 - (53%) Gaps:26/274 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 KLRAVRVLGQGTFGRVFLCHQNEVRGQPERKVCVKRIIVRN-PKTELGLIKEEVYIISQLRHPHI 70
            |...:||:|:|.||.|.||    :|...::.|.:|:|.|.. .|.|....:.|..::..|.||::
Mouse     3 KYERIRVVGRGAFGIVHLC----LRKADQKLVILKQIPVEQMTKEERQAAQNECQVLKLLNHPNV 63

  Fly    71 VEFLRSFSHAGTVNIVMEYVPNGTLRDVIQQLPSGTGGVNQERLMGYFRDMVVGLEYLHIRCVIH 135
            :|:..:|.....:.|.|||.|.|||.:.||:..:..  :.:|.::.:|..:::.|.::|...::|
Mouse    64 IEYYENFLEDKALMIAMEYAPGGTLAEFIQKRCNSL--LEEETILHFFVQILLALHHVHTHLILH 126

  Fly   136 RDIKPENMLLDANDR-VKIADFGIANVHAPSTQLQAGMGTPMYMAPEAMSSQGK-VDFKSDVWSL 198
            ||:|.:|:|||.:.. |||.||||:.:.:..::....:|||.|::||.  .:|| .:.|||:|:|
Mouse   127 RDLKTQNILLDKHRMVVKIGDFGISKILSSKSKAYTVVGTPCYISPEL--CEGKPYNQKSDIWAL 189

  Fly   199 GLVLYELC-LGRSPFAAFLDKNATPALLHTVVQALVRPRLDCQLIRRLYDPVWAQVCELMVVYEQ 262
            |.|||||. |.|:..||.|     |||:..::.....|      |...|.|...|:...::..|.
Mouse   190 GCVLYELASLKRAFEAANL-----PALVLKIMSGTFAP------ISDRYSPELRQLVLSLLSLEP 243

  Fly   263 ERRICLPDIFHLDA 276
            .:|   |.:.|:.|
Mouse   244 AQR---PPLSHIMA 254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pngNP_477492.1 S_TKc 11..271 CDD:214567 86/263 (33%)
Nek8XP_006532246.1 STKc_Nek8 3..258 CDD:270859 89/274 (32%)
ATS1 319..653 CDD:444065
RCC1 637..679 CDD:395335
Blue background indicates that the domain is not in the aligned region.

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