Protein Alignment png and NEK7

DIOPT Version :10

• Sequence 1: NP_477492.1
• Gene: png / 31084
• FlyBaseID: FBgn0000826
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: XP_016855833.1
• Gene: NEK7 / 140609
• HGNCID: 13386
• Length: 310
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 86/297 - (28%)
• Similarity: 142/297 - (47%)
• Gaps: 49/297 - (16%)

  Fly     2 ELGDSKLRAVRV---LGQGTFGRVF--LCHQNEVRGQPERKVCVKRIIV---RNPKTELGLIKEE 58
            ::|.:.|...|:   :|:|.|..|:  .|   .:.|.|   |.:|::.:   .:.|.....|| |
Human    25 DMGYNTLANFRIEKKIGRGQFSEVYRAAC---LLDGVP---VALKKVQIFDLMDAKARADCIK-E 82

  Fly    59 VYIISQLRHPHIVEFLRSFSHAGTVNIVMEYVPNGTLRDVIQQL---------------PSGTGG 108
            :.::.||.||:::::..||.....:|||:|....|.|..:|:.|               |..|
Human    83 IDLLKQLNHPNVIKYYASFIEDNELNIVLELADAGDLSRMIKFLFLIFKKHFKKQKRLIPERT-- 145

  Fly   109 VNQERLMGYFRDMVVGLEYLHIRCVIHRDIKPENMLLDANDRVKIADFGIAN-VHAPSTQLQAGM 172
                 :..||..:...||::|.|.|:||||||.|:.:.|...||:.|.|:.. ..:.:|...:.:
Human   146 -----VWKYFVQLCSALEHMHSRRVMHRDIKPANVFITATGVVKLGDLGLGRFFSSKTTAAHSLV 205

  Fly   173 GTPMYMAPEAMSSQGKVDFKSDVWSLGLVLYELCLGRSPFAAFLDKNATPALLHTVVQALVRPRL 237
            |||.||:||.:...| .:||||:||||.:|||:...:|||  :.||....:|...:.|....|
Human   206 GTPYYMSPERIHENG-YNFKSDIWSLGCLLYEMAALQSPF--YGDKMNLYSLCKKIEQCDYPP-- 265

  Fly   238 DCQLIRRLYDPVWAQVCELMVVYEQERRICLPDIFHL 274
               |....|.....|:..:.:..:.|:|   ||:.::
Human   266 ---LPSDHYSEELRQLVNMCINPDPEKR---PDVTYV 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
png	NP_477492.1	S_TKc	11..271	CDD:214567	83/283 (29%)
NEK7	XP_016855833.1	STKc_Nek6_7	33..302	CDD:270863	84/289 (29%)