Protein Alignment CG12773 and VHC1

DIOPT Version :10

• Sequence 1: NP_569905.1
• Gene: CG12773 / 31082
• FlyBaseID: FBgn0024365
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_009794.3
• Gene: VHC1 / 852537
• SGDID: S000000439
• Length: 1120
• Species: Saccharomyces cerevisiae
• Alignment Length: 592
• Identity: 140/592 - (23%)
• Similarity: 240/592 - (40%)
• Gaps: 153/592 - (25%)

  Fly    93 GTWDGVFTSCLINVFGVIVFLRSGWIVAQAGILNAVLIIFCTVVIALVSVLSAIGICERCRVESG 157
            ||:||||....:||..:::|||.|:|:.|.||:..:.::..:..|.|::.||...|.....|..|
Yeast    64 GTYDGVFVPTALNVLSILMFLRFGFILGQLGIICTIGLLLLSYTINLLTTLSISAISTNGTVRGG 128

  Fly   158 GVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVMGFGESMAGLVG--LEGSKWAIRG------- 213
            |.|::|:.:||..|||::||::..||.....:|.:|..|.:...:|  .:|...|..|
Yeast   129 GAYYMISRSLGPEFGGSIGLVFFLGQVFNAGMNAVGIIEPLLYNLGYSAQGEPPAALGELLPRGH 193

  Fly   214 ---FATAAVLLLGCINVA--GVKWVIKLQFILLMILLIS----ALDFMVGSFTSEASGGFNGWAS 269
               |..|.|:|..|.:||  |.:.|.:...||.::|..|    .|..::.|..:|....:.|.:.
Yeast   194 WHEFTYATVILFLCFSVAFVGSQTVSRAGNILFLVLAASIFSIPLSALIRSPFTEGGISYTGPSW 258

  Fly   270 GNFVENLWPKYDDG---------YSWFRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPNGTLAAF 325
            ..|.:||.|....|         .::..:||||||...|:.:|..||.:||.||..||.|||...
Yeast   259 QTFHDNLLPHLTKGAAGSLLKGKETFNDLFGVFFPATAGIFAGAGMSSELRKPSKSIPKGTLWGL 323

  Fly   326 GTSTFLYLVFVLFLGATCQRSFLYTDYMISVKVSAVHFLLLAGIYVSSMSSCLGAMYGTPRVLQS 390
            ..:...|.|.|..:|.:..|..||.:..|...:|:|.:::..|...:|:.|.:..|.|...||::
Yeast   324 LFTFICYAVVVFSMGCSIPRRSLYDEVQIIQTISSVQWVIFMGEMATSLFSIIVGMLGAAYVLEA 388

  Fly   391 IAKESVIPGIDILGKGRGPNKVPLYAMAIVALVTVTFIIVGDINFLAPIVTMPFLLTYACIDYAY 455
            |||:::|||::|....      |||::....::| ...:..|:|.:|..:||.||:|:..::.|.
Yeast   389 IAKDNIIPGLEIFAHS------PLYSLIFTWILT-QLCLFSDVNKIATFITMTFLMTFVVMNLAC 446

  Fly   456 FALAQTFDIQEQREERFRIQASSPSYETRRYGSVSDTGNDLDLLFPDRVRHKNLQSPQNSPLHQT 520
            |.|.               .:|:|::
Yeast   447 FLLG---------------ISSAPNF--------------------------------------- 457

  Fly   521 VPLEFDNEGPSTSNQAQSSERRTGHEADTTLAVEQAVAQAGVEQDQGDEAEPIAPIRPPIHSKTK 585
                                                                    ||...
Yeast   458 --------------------------------------------------------RPSFK---- 462

  Fly   586 NWYSGYCNRWASLLGAFTKLLVMLLVNWYYALTCFLVVFVVWFYVGTANPAVKPGLTAEFNFFAW 650
                 |.||:.:.:||...::.||:|:...|...||.:.:::.::...:|....|..::...:..
Yeast   463 -----YFNRYTTAIGALLSVVAMLIVDGISASVLFLAMILLFLFIHYFSPPKSWGDVSQSLIYHQ 522

  Fly   651 LKSVIFR 657
            ::..:.|
Yeast   523 VRKYLLR 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12773	NP_569905.1	AA_permease_2	88..>456	CDD:459263	120/389 (31%)
VHC1	NP_009794.3	AA_permease_2	45..824	CDD:459263	140/592 (24%)