Protein Alignment CG12773 and SLC12A2

DIOPT Version :9

• Sequence 1: NP_001284773.1
• Gene: CG12773 / 31082
• FlyBaseID: FBgn0024365
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_001037.1
• Gene: SLC12A2 / 6558
• HGNCID: 10911
• Length: 1212
• Species: Homo sapiens
• Alignment Length: 604
• Identity: 166/604 - (27%)
• Similarity: 264/604 - (43%)
• Gaps: 172/604 - (28%)

  Fly    90 VLFGTWDGVFTSCLINVFGVIVFLRSGWIVAQAGILNAVLIIFCTVVIALVSVLSAIGICERCRV 154
            |.||...||...|::|::||::|:|..|||.||||..:||:|....|:..::.||...|.....|
Human   283 VKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFV 347

  Fly   155 ESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVMGFGESMAGLVGLEGSKWAIRGF----- 214
            ..||.|:||:.:||..||||:||::.|..||..|:.|:||.|::..|: .|.|...|...
Human   348 RGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELL-KEHSILMIDEINDIRI 411

  Fly   215 --ATAAVLLLGCINVAGVKWVIKLQFILLMILLISALDFMVGSF---TSEASGGFNGWASGNFVE 274
              |...|:||| |:|||::|..|.|.:||:|||::..||::|:|   .|:...||.|:.|..|.|
Human   412 IGAITVVILLG-ISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLESKKPKGFFGYKSEIFNE 475

  Fly   275 NLWPKYDDGYSWFRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPNGTLAAFGTSTFLYLVFVLFL 339
            |..|.:.:..::|.||.:|||..||:|:|.|:||||..|.:.||.|||.|...:|.:|:...:.:
Human   476 NFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSV 540

  Fly   340 G------------------------ATCQRSF-------------LYTDYMISVKVSAVHFLLLA 367
            |                        |.|:.:|             |..::.:...||....|:.|
Human   541 GSCVVRDATGNVNDTIVTELTNCTSAACKLNFDFSSCESSPCSYGLMNNFQVMSMVSGFTPLISA 605

  Fly   368 GIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGIDILGKGRGPNKVPLYAMAIVALVTVTFIIVGD 432
            ||:.:::||.|.::...|::.|::.|:::.|...:..||.|.|..||....:..|:.:.||::.:
Human   606 GIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAE 670

  Fly   433 INFLAPIVTMPFLLTYACIDYAYFALAQTFDIQEQREERFRIQASSPSYETRRYGSVSDTGNDLD 497
            :|.:|||::..||.:||.|:::.|
Human   671 LNVIAPIISNFFLASYALINFSVF----------------------------------------- 694

  Fly   498 LLFPDRVRHKNLQSPQNSPLHQTVPLEFDNEGPSTSNQAQSSERRTGHEADTTLAVEQAVAQAGV 562
                    |.:|
Human   695 --------HASL----------------------------------------------------- 698

  Fly   563 EQDQGDEAEPIAPIRPPIHSKTKNWYSG--YCNRWASLLGAFTKLLVMLLVNWYYALTCFLVVFV 625
                               :|:..|...  |.|.|.|||||....:||.::||:.||..:::|..
Human   699 -------------------AKSPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYVIVLG 744

  Fly   626 VWFYVGTANPAVKPGLTAE 644
            ::.||....|.|..|.:.:
Human   745 LYIYVTYKKPDVNWGSSTQ 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12773	NP_001284773.1	2a30	88..>456	CDD:273347	141/412 (34%)
SLC12A2	NP_001037.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..81
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	112..138
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	150..193
		2a30	216..1212	CDD:273347	166/604 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	962..989

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2083
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810