DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12773 and can1

DIOPT Version :9

Sequence 1:	NP_001284773.1	Gene:	CG12773 / 31082	FlyBaseID:	FBgn0024365	Length:	712	Species:	Drosophila melanogaster
Sequence 2:	NP_001342720.1	Gene:	can1 / 2540830	PomBaseID:	SPBC18H10.16	Length:	1050	Species:	Schizosaccharomyces pombe

Alignment Length:	446	Identity:	133/446 - (29%)
Similarity:	225/446 - (50%)	Gaps:	55/446 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 WRSNFF-----ISQPVLF------------GTWDGVFTSCLINVFGVIVFLRSGWIVAQAGILNA 127
            :|||.|     :|:.|.|            ||::|.|....:||..::::||..||:.:||:|..
pombe    48 YRSNSFNELPPLSRSVTFAENEQPNEAVKLGTFEGCFIPTTLNVLSILLYLRFPWIIGEAGVLKT 112

  Fly   128 VLIIFCTVVIALVSVLSAIGICERCRVESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVM 192
            :|::|.:..:.:.:.||...||....|..||.|:.::.::|...||::||::..||.:...:|:.
pombe   113 LLMLFISYAVGIFTSLSISAICTNGMVRGGGAYYAVSRSIGPELGGSIGLIFYVGQILNTGMNIS 177

  Fly   193 GFGESMAGLVGLEG---SKWAIRGF-----ATAAVLLLGCINVA-GVKWVIKLQFILLMILLISA 248
            ||.|.:..:.|.|.   |::...|:     .|..||.:.||... |.....|....|.:::::|.
pombe   178 GFVEPIISIFGKESGTISQFLPEGYWWVFLYTTCVLAMCCILCCLGSAIFAKASNALFVVIILST 242

  Fly   249 LDFMVGSF------TSEASGGFNGWASGNFVENLWPKYDD-----GYSWFR-VFGVFFPTVTGVL 301
            :...:.|.      .......|.|......::||...|.:     ||..|: .||||||...|:|
pombe   243 ISIPISSIFVHPFKDPSLLVHFTGLKWSTLMKNLASAYTENEKGTGYESFKSTFGVFFPATAGLL 307

  Fly   302 SGINMSGDLRAPSTDIPNGTLAAFGTSTFLYLVFVLFLGATCQRSFLYTDYMISVKVSAVHFLLL 366
            :|.:|||||:|||..||.||:::..|:..|||:.:|.:||:..|:.|..|..:...:|.....::
pombe   308 AGASMSGDLKAPSRSIPKGTISSQATTFLLYLLVILCVGASVTRTGLLLDMDVMEHISLHPLFII 372

  Fly   367 AGIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGIDILGKGRGPNKVPLYAMAIVALVTVTFIIVG 431
            :||..|...|....::|..::||:||::.:|||:....||...:.:|..|:.:..|:| ...:..
pombe   373 SGILSSGAFSSFMGIFGAAKLLQAIARDDLIPGMFFFAKGSSYDDIPYVAIGVTYLIT-QISLFW 436

  Fly   432 DINFLAPIVTMPFLLTYACIDYAYFALAQTFDIQEQREERFRIQASSPSYE-TRRY 486
            |||.|:.::||.||||:..|:.:.|.|              || :|:|::. |.||
pombe   437 DINMLSSMITMTFLLTFGFINLSCFLL--------------RI-SSTPNFRPTFRY 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12773	NP_001284773.1	2a30	88..>456	CDD:273347	119/400 (30%)
can1	NP_001342720.1	SLC12	57..818	CDD:332077	129/437 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11827
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.970