Protein Alignment CG12773 and Slc12a1

DIOPT Version :9

• Sequence 1: NP_001284773.1
• Gene: CG12773 / 31082
• FlyBaseID: FBgn0024365
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_001257546.1
• Gene: Slc12a1 / 25065
• RGDID: 3685
• Length: 1095
• Species: Rattus norvegicus
• Alignment Length: 619
• Identity: 160/619 - (25%)
• Similarity: 258/619 - (41%)
• Gaps: 165/619 - (26%)

  Fly    72 GEQGDKPWWRSNFFISQPVLFGTWDGVFTSCLINVFGVIVFLRSGWIVAQAGILNAVLIIFCTVV 136
            |..||:........::..|.||...||...|::|::||::|:|..|||.:|||...||||..:.:
  Rat   153 GMPGDEQAENKEEDVTGVVKFGWVKGVLVRCMLNIWGVMLFIRLSWIVGEAGIGLGVLIILLSTM 217

  Fly   137 IALVSVLSAIGICERCRVESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVMGFGESMAGL 201
            :..::.||...|.....|..||.|:||:.:||..|||::||::.|..||..|:.|:||.|::..|
  Rat   218 VTSITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGSIGLIFAFANAVAVAMYVVGFAETVVDL 282

  Fly   202 VGLEGSKWA-----IRGFATAAVLLLGCINVAGVKWVIKLQFILLMILLISALDFMVG----SFT 257
            :....|...     ||...:..|::|..|:|||::|..|.|.|||:||||:..:|.:|    |..
  Rat   283 LKESDSMMVDPTNDIRIIGSITVVILLGISVAGMEWEAKAQVILLVILLIAIANFFIGTVIPSNN 347

  Fly   258 SEASGGFNGWASGNFVENLWPKYDDGYSWFRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPNGTL 322
            .:.|.||..:.:..|.||..|.:.:|..:|.||.:|||..||:|:|.|:||||..|...||.||:
  Rat   348 EKKSRGFFNYQASIFAENFGPSFTEGEGFFSVFAIFFPAATGILAGANISGDLEDPQDAIPRGTM 412

  Fly   323 AAFGTSTFLYLVFVLFLGA---------------------------------TCQRS----FLYT 350
            .|...:|..|:...:.:.|                                 .||..    .|..
  Rat   413 LAIFITTVAYIGVAICVAACVVRDATGSMNDTVVSGMNCNGSAACGLGYDFSRCQHEPCQYGLMN 477

  Fly   351 DYMISVKVSAVHFLLLAGIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGIDILGKGRGPNKVPLY 415
            ::.:...||....|:.|||:.:::||.|.::...|:|.|::.|:::..|:....||.|.|..||.
  Rat   478 NFQVMSMVSGFGPLITAGIFSATLSSALASLVSAPKVFQALCKDNIFKGLQFFAKGYGKNNEPLR 542

  Fly   416 AMAIVALVTVTFIIVGDINFLAPIVTMPFLLTYACIDYAYFALAQTFDIQEQREERFRIQASSPS 480
            ...:..::.:.||::.::|.:|||::..||.:||.|:::.|..:               .|.||.
  Rat   543 GYFLTFVIAMAFILIAELNVIAPIISNFFLASYALINFSCFHAS---------------YAKSPG 592

  Fly   481 YETRRYGSVSDTGNDLDLLFPDRVRHKNLQSPQNSPLHQTVPLEFDNEGPSTSNQAQSSERRTGH 545
            :
  Rat   593 W---------------------------------------------------------------- 593

  Fly   546 EADTTLAVEQAVAQAGVEQDQGDEAEPIAPIRPPIHSKTKNWYSGYCNRWASLLGAFTKLLVMLL 610
                                           ||..         |..|.|.||.||.....||.:
  Rat   594 -------------------------------RPAY---------GIYNMWVSLFGAILCCAVMFV 618

  Fly   611 VNWYYALTCFLVVFVVWFYVGTANPAVKPGLTAE 644
            :||:.|:..:::...::.||....|.|..|.:.:
  Rat   619 INWWAAVITYVIELFLYIYVTYKKPDVNWGSSTQ 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12773	NP_001284773.1	2a30	88..>456	CDD:273347	134/413 (32%)
Slc12a1	NP_001257546.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..45
		AA_permease_N	86..152	CDD:285588
		2a30	100..1095	CDD:273347	160/619 (26%)
		SLC12	690..1095	CDD:281515

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2083
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810