Protein Alignment CG12773 and Slc12a2

DIOPT Version :10

• Sequence 1: NP_569905.1
• Gene: CG12773 / 31082
• FlyBaseID: FBgn0024365
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_033220.2
• Gene: Slc12a2 / 20496
• MGIID: 101924
• Length: 1206
• Species: Mus musculus
• Alignment Length: 175
• Identity: 32/175 - (18%)
• Similarity: 55/175 - (31%)
• Gaps: 75/175 - (42%)

  Fly    98 WSWAPN-CYYSSHVFEVSL-------------------YNVPLEELLKIRKVNILINGKVI---- 138
            |..:.| |.|....:|..|                   |:.|:.          ..:|:::
Mouse    21 WIGSSNGCLYPGGDYEFKLKLDKNVIPALAGCAQIPCAYSAPMR----------THSGRLVWFSG 75

  Fly   139 --DLNIKQVMPKLKDGLTICVQPVYWYNQFQNIILFIESWRNQGASHFIVYFHSSTKEVKMVLDH 201
              |..|.....:.||||   ::|:....:..:|:|    |...|        |...:|..::|:
Mouse    76 SPDFPISPRDMERKDGL---LRPLASILEECSIVL----WDFSG--------HERVEEYGVMLE- 124

  Fly   202 YQKLGILTIMPWPTFGTLPTQFPNINSQVY--RVGHNLAANLCVL 244
                       |.|..|          .||  ||..:.:|.:|.:
Mouse   125 -----------WGTNET----------HVYDERVAVSYSAGMCFI 148

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12773	NP_569905.1	AA_permease_2	88..>456	CDD:459263	32/175 (18%)
Slc12a2	NP_033220.2	PRK07764	<3..74	CDD:236090	9/62 (15%)
		RFXV motif 1. /evidence=ECO:0000269|PubMed:14563843	78..81		1/2 (50%)
		RFXV motif 2. /evidence=ECO:0000269|PubMed:14563843	134..137		0/2 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..188		1/5 (20%)
		2a30	210..1206	CDD:273347
		Scissor helix. /evidence=ECO:0000250|UniProtKB:P55011	755..772
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	954..987