Protein Alignment CG12773 and Slc12a2

DIOPT Version :9

• Sequence 1: NP_001284773.1
• Gene: CG12773 / 31082
• FlyBaseID: FBgn0024365
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_033220.2
• Gene: Slc12a2 / 20496
• MGIID: 101924
• Length: 1206
• Species: Mus musculus
• Alignment Length: 604
• Identity: 165/604 - (27%)
• Similarity: 264/604 - (43%)
• Gaps: 172/604 - (28%)

  Fly    90 VLFGTWDGVFTSCLINVFGVIVFLRSGWIVAQAGILNAVLIIFCTVVIALVSVLSAIGICERCRV 154
            |.||...||...|::|::||::|:|..|||.||||..:|::|....|:..::.||...|.....|
Mouse   277 VKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVVVIAMATVVTTITGLSTSAIATNGFV 341

  Fly   155 ESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVMGFGESMAGLVGLEGSKWAIRGF----- 214
            ..||.|:||:.:||..||||:||::.|..||..|:.|:||.|::..|: .|.|...|...
Mouse   342 RGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELL-KEHSILMIDEINDIRI 405

  Fly   215 --ATAAVLLLGCINVAGVKWVIKLQFILLMILLISALDFMVGSFTSEAS---GGFNGWASGNFVE 274
              |...|:||| |:|||::|..|.|.:||:|||::..||::|:|.|..|   .||.|:.|..|.|
Mouse   406 IGAITVVILLG-ISVAGMEWEAKAQIVLLVILLLAIADFVIGTFISLESKKPKGFFGYKSEIFNE 469

  Fly   275 NLWPKYDDGYSWFRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPNGTLAAFGTSTFLYLVFVLFL 339
            |..|.:.:..::|.||.:|||..||:|:|.|:||||..|.:.||.|||.|...:|.:|:...:.:
Mouse   470 NFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTVVYIGIAVSV 534

  Fly   340 G------------------------ATCQRSF-------------LYTDYMISVKVSAVHFLLLA 367
            |                        |.|:.:|             |..::.:...||....|:.|
Mouse   535 GSCVVRDATGNVNDTITTELTNCTSAACKLNFDFSYCESNTCSYGLMNNFQVMSMVSGFAPLISA 599

  Fly   368 GIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGIDILGKGRGPNKVPLYAMAIVALVTVTFIIVGD 432
            ||:.:::||.|.::...|::.|::.|:::.|...:..||.|.|..||....:..|:.:.||::.:
Mouse   600 GIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAE 664

  Fly   433 INFLAPIVTMPFLLTYACIDYAYFALAQTFDIQEQREERFRIQASSPSYETRRYGSVSDTGNDLD 497
            :|.:|||::..||.:||.|:::.|
Mouse   665 LNVIAPIISNFFLASYALINFSVF----------------------------------------- 688

  Fly   498 LLFPDRVRHKNLQSPQNSPLHQTVPLEFDNEGPSTSNQAQSSERRTGHEADTTLAVEQAVAQAGV 562
                    |.:|
Mouse   689 --------HASL----------------------------------------------------- 692

  Fly   563 EQDQGDEAEPIAPIRPPIHSKTKNWYSG--YCNRWASLLGAFTKLLVMLLVNWYYALTCFLVVFV 625
                               :|:..|...  |.|.|.||:||....:||.::||:.||..:::|..
Mouse   693 -------------------AKSPGWRPAFKYYNMWISLIGAILCCIVMFVINWWAALLTYVIVLG 738

  Fly   626 VWFYVGTANPAVKPGLTAE 644
            ::.||....|.|..|.:.:
Mouse   739 LYIYVTYKKPDVNWGSSTQ 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12773	NP_001284773.1	2a30	88..>456	CDD:273347	141/412 (34%)
Slc12a2	NP_033220.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	144..188
		AA_permease_N	196..257	CDD:285588
		2a30	210..1206	CDD:273347	165/604 (27%)
		SLC12	795..1206	CDD:281515
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	954..987

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2083
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810