Protein Alignment CG12773 and F10E7.9

DIOPT Version :9

• Sequence 1: NP_001284773.1
• Gene: CG12773 / 31082
• FlyBaseID: FBgn0024365
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_495469.2
• Gene: F10E7.9 / 174167
• WormBaseID: WBGene00017350
• Length: 603
• Species: Caenorhabditis elegans
• Alignment Length: 664
• Identity: 242/664 - (36%)
• Similarity: 361/664 - (54%)
• Gaps: 101/664 - (15%)

  Fly    67 NEIFA-GEQGDK---PWWRSNFFISQPVLFGTWDGVFTSCLINVFGVIVFLRSGWIVAQAGILNA 127
            :.||: ||..|.   |||:........||||||||||.:.::|:||:|||||.||||..||:.|:
 Worm    18 DSIFSQGETADSSQLPWWQRTILTKDKVLFGTWDGVFATVMVNIFGIIVFLRLGWIVGTAGVANS 82

  Fly   128 VLIIFCTVVIALVSVLSAIGICERCRVESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVM 192
            :|::.....:||::|.|||||.|||:::|||:|||::|.||.:.|||:|::|.|||||...|..:
 Worm    83 ILLLGICTSLALITVFSAIGIVERCQIKSGGIYFLVSHVLGHQIGGAIGIIYAFGQAVATGLVAV 147

  Fly   193 GFGESMAGLVGLEGSKWAIRGFATAAVLLLGCINVAGVKWVIKLQFILLMILLISALDFMVGS-F 256
            |||||:|.|...| ||..|:|.|...:::|..:|.|||.||::||.:||:.:.::..||:.|: |
 Worm   148 GFGESVAHLFESE-SKIMIKGIAILTLMVLTAVNTAGVTWVVRLQIVLLLTIALAVTDFIFGALF 211

  Fly   257 TSEASGGFNGWASGNFVENLWPKYDDGY-----------------SWFRVFGVFFPTVTGVLSGI 304
            :||...|...::|    |.:....|..|                 |:|.||||||....|||:|:
 Worm   212 SSEPESGVFRFSS----ERIRVNADSHYEAVNCSIIGIPRQIPEQSFFTVFGVFFANFLGVLAGV 272

  Fly   305 NMSGDLRAPSTDIPNGTLAAFGTSTFLYLVFVLFLGATCQRSFLYTDYMISVKVSAVHFLLLAGI 369
            ||||||:.|...||.|.|:|.|.|:.:..:|::.||....|.||..|.|||.||:....:.|.|:
 Worm   273 NMSGDLKDPHKSIPLGELSAVGVSSTICFIFIMILGGVGDRMFLLCDVMISEKVALTGIVFLVGL 337

  Fly   370 YVSSMSSCLGAMYGTPRVLQSIAKESVIPGIDILGKGRGPNKVPLYAMAIVALVTVTFIIVGDIN 434
            ||.|:||.:|::.|||||||.||:|.:||.:::|.:|.|||..|:.|..::..|...|:::||:|
 Worm   338 YVCSLSSTVGSLLGTPRVLQGIAEEGIIPCLNVLARGVGPNDNPVLAGYLLMGVASLFVLLGDLN 402

  Fly   435 FLAPIVTMPFLLTYACIDYAYFALAQTFDIQEQREERFRIQASSPSYETRRYGSVSDTGNDLDLL 499
            .||.:.|||||:|||.::|:|.:||.::|:...:.        :...||..|||.:.. |||:.|
 Worm   403 QLAILSTMPFLITYAYVNYSYVSLAMSYDLATVQH--------ADEVETVGYGSTNKM-NDLNEL 458

  Fly   500 FPDRVRHKNLQSPQNSPLHQTVPLEFDNEGPSTSNQAQSSERRTGHEADTTLAVEQAVAQAGVEQ 564
            ||:| |..|:.|                          :.|..||
 Worm   459 FPER-RDVNITS--------------------------TEETETG-------------------- 476

  Fly   565 DQGDEAEPIAPIRPPIHSKTKNWYSGYCNRWASLLGAFTKLLVMLLVNWYYALTCFLVVFVVWFY 629
                           |.|:...|||.:.||:.|.||....|.::||:::::|:..|:.:..:::|
 Worm   477 ---------------IISQEATWYSMFSNRYVSFLGFLVNLAILLLIHFWFAVAHFVALIALYWY 526

  Fly   630 VGTANPAVKPGLTAEFNFFAWLKSVIFRCFGKRMNEYEQIVVTPSCPGVDLSPTQLNEQNEDFRP 694
            :|...|...||::. |:.....|:|.......|......:..|....||  |.:|.||.|.|::.
 Worm   527 IGRVCPTCGPGIST-FSLCHMFKTVFSSLDSLRSGATTILPETTFTSGV--SSSQQNEANPDYQD 588

  Fly   695 RPNYHHSSVIEGRL 708
            |..||||..:..:|
 Worm   589 RRQYHHSENVSHQL 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12773	NP_001284773.1	2a30	88..>456	CDD:273347	173/385 (45%)
F10E7.9	NP_495469.2	2a30	47..>557	CDD:273347	216/586 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158649
Domainoid	1	1.000	319	1.000	Domainoid score	I671
eggNOG	1	0.900	-	-		E2759_KOG2083
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11628
Inparanoid	1	1.050	440	1.000	Inparanoid score	I933
Isobase	1	0.950	-	0.946395	Normalized mean entropy	S3116
OMA	1	1.010	-	-		QHG48035
OrthoDB	1	1.010	-	-		D344013at33208
OrthoFinder	1	1.000	-	-		FOG0007328
OrthoInspector	1	1.000	-	-		oto17425
orthoMCL	1	0.900	-	-		OOG6_108582
Panther	1	1.100	-	-	LDO	PTHR11827
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3761
SonicParanoid	1	1.000	-	-		X5443
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790