Protein Alignment CG12773 and Slc12a6

DIOPT Version :9

• Sequence 1: NP_001284773.1
• Gene: CG12773 / 31082
• FlyBaseID: FBgn0024365
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: NP_598410.2
• Gene: Slc12a6 / 107723
• MGIID: 2135960
• Length: 1150
• Species: Mus musculus
• Alignment Length: 578
• Identity: 150/578 - (25%)
• Similarity: 242/578 - (41%)
• Gaps: 154/578 - (26%)

  Fly    25 GDE--DGDVAVTSFRQRTNNNTGGFVDLGNEYT-YAAGGHHASGANEIFAGEQGDKPWWRSNFFI 86
            |||  |.::|:......|.......::....|| ...|......|..|..|::  ||
Mouse   125 GDEYFDKNLALFEEEMDTRPKVSSLLNRMANYTNLTQGAKEHEEAENITEGKK--KP-------- 179

  Fly    87 SQPVLFGTWDGVFTSCLINVFGVIVFLRSGWIVAQAGILNAVLIIF----CTVVIAL-VSVLSAI 146
            ::....||:.||:..||.|:||||:|||..|:|..||||.|..|:.    ||::.|: :|.::..
Mouse   180 TKSPQMGTFMGVYLPCLQNIFGVILFLRLTWVVGTAGILQAFAIVLICCCCTMLTAISMSAIATN 244

  Fly   147 GICERCRVESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVMG------------------ 193
            |:     |.:||.||:|:..||..||||:||.:..|.....|:.::|
Mouse   245 GV-----VPAGGSYFMISRALGPEFGGAVGLCFYLGTTFAAAMYILGAIEIFLVYIVPRAAIFRS 304

  Fly   194 ---FGESMAGLVGLEGSKWAIRGFATAAVLLLGCINVAGVKWVIKLQFILLMILLISALDFMVGS 255
               ..||.|.|..:       |.:.||.::|:..:...||::|.|...:.|..:::|.|....|:
Mouse   305 DDALKESAAMLNNM-------RVYGTAFLVLMVLVVFIGVRYVNKFASLFLACVIVSILAIYAGA 362

  Fly   256 ---------------------------------------------FTSEASGGFN---------- 265
                                                         |...:|..||
Mouse   363 IKSSFAPPHFPVCMLGNRTLSSRHLDICSKTKEVDNMTVPSKLWGFFCNSSQFFNATCDEYFVHN 427

  Fly   266 ---------GWASGNFVENLWPKY----------------------------DDGYSWFRVFGVF 293
                     |.|||...||||..|                            |...|:..:.|:|
Mouse   428 NVISIQGIPGLASGIITENLWSNYLPKGEIIEKPSAKSSDVLGNLNHEYVLADITTSFTLLVGIF 492

  Fly   294 FPTVTGVLSGINMSGDLRAPSTDIPNGTLAAFGTSTFLYLVFVLFLGATCQRSFLYTDYMISVKV 358
            ||:|||:::|.|.||||:.....||.||:.|..|::|:||..|:..||..:...|...:..:||.
Mouse   493 FPSVTGIMAGSNRSGDLKDAQKSIPIGTILAILTTSFVYLSNVVLFGACIEGVVLRDKFGDAVKG 557

  Fly   359 SAV--------HFLLLAGIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGIDILGKGRGPNKVPLY 415
            :.|        .::::.|.:.|:..:.|.::.|.||:||:|||:::||.:.:.|..:. |..|.:
Mouse   558 NLVVGTLSWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHSKA-NGEPTW 621

  Fly   416 AMAIVALVTVTFIIVGDINFLAPIVTMPFLLTYACIDYAYFALAQTFDIQEQREERFR 473
            |:.:.|.:....|::..::.:|||::|.||:.|..::.|  ...||.........|||
Mouse   622 ALLLTAAIAELGILIASLDLVAPILSMFFLMCYLFVNLA--CALQTLLRTPNWRPRFR 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12773	NP_001284773.1	2a30	88..>456	CDD:273347	131/493 (27%)
Slc12a6	NP_598410.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..108
		2a30	109..1150	CDD:273347	150/578 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..181		6/29 (21%)
		SLC5-6-like_sbd	209..>360	CDD:294310	45/162 (28%)
		SLC12	774..1150	CDD:281515

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910