Protein Alignment CG12773 and slc12a8

DIOPT Version :9

• Sequence 1: NP_001284773.1
• Gene: CG12773 / 31082
• FlyBaseID: FBgn0024365
• Length: 712
• Species: Drosophila melanogaster
• Sequence 2: XP_031749017.1
• Gene: slc12a8 / 100488646
• XenbaseID: XB-GENE-997779
• Length: 723
• Species: Xenopus tropicalis
• Alignment Length: 694
• Identity: 288/694 - (41%)
• Similarity: 417/694 - (60%)
• Gaps: 71/694 - (10%)

  Fly    77 KPWWRSNFFISQPVLFGTWDGVFTSCLINVFGVIVFLRSGWIVAQAGILNAVLIIFCTVVIALVS 141
            :|||:...|:.:||||||||||||||:||:|||::|||:||:|...|:|..|:::...:::|||:
 Frog    38 RPWWKIQLFVWEPVLFGTWDGVFTSCMINIFGVVLFLRTGWLVGNTGVLLGVVLVSFVILVALVT 102

  Fly   142 VLSAIGICERCRVESGGVYFLIAHTLGSRFGGALGLLYCFGQAVGCALNVMGFGESMAGLVGLEG 206
            |||.||:||||.:.|||||.:::..||.:.||.:||||.|||.|..|:.:.||.||::.|:.||
 Frog   103 VLSGIGVCERCSIGSGGVYSMVSTVLGGKVGGTVGLLYIFGQCVAGAMYITGFAESISDLLNLE- 166

  Fly   207 SKWAIRGFATAAVLLLGCINVAGVKWVIKLQFILLMILLISALDFMVGSFTS-EASGGFNGWASG 270
            :.|.:||.:.|.::.|..||:|||||:|:||.:||::|.||.|||::||||. :...||.|::..
 Frog   167 NMWVVRGISLAVLVALLGINLAGVKWIIRLQLLLLLLLAISTLDFVIGSFTHLDPENGFVGYSEE 231

  Fly   271 NFVENLWPKYDDGYSWFRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPNGTLAAFGTSTFLYLVF 335
            ....|.:|.|..|.::|.|||||||..|||:.|.||||||:.||.:||.|:|||.|||.|||:||
 Frog   232 LLRTNTFPDYSPGETFFTVFGVFFPAATGVMVGFNMSGDLQRPSRNIPVGSLAAIGTSWFLYVVF 296

  Fly   336 VLFLGATCQRSFLYTDYMISVKVSAVHFLLLAGIYVSSMSSCLGAMYGTPRVLQSIAKESVIPGI 400
            |..|||.|.|.||..::||:.|||.|..|.|.|:|:||::||:|.:||.||:||.||:|.|||.:
 Frog   297 VFLLGAICTRDFLRYEFMIAEKVSLVGALFLLGLYISSLASCMGGLYGAPRILQCIAQEKVIPAL 361

  Fly   401 DILGKGRGPNKVPLYAMAIVALVTVTFIIVGDINFLAPIVTMPFLLTYACIDYAYFALAQTFDIQ 465
            ..||:|:||||.|:.|:.|..|:|:.|:.:|.:|.||||||:.|:|||:.:||:||::..::.::
 Frog   362 SFLGRGKGPNKTPVAAIFITGLLTMAFVFIGQVNVLAPIVTINFMLTYSAVDYSYFSVTMSYRMR 426

  Fly   466 EQREERFRIQA------------SSPSY--------------------ETRRYGSVSDTGNDLDL 498
            ...::..:.|:            .|.||                    :|...||.|....||.:
 Frog   427 HSPKKNGKPQSRGMSSTQPLILNKSTSYGSNGTLLEFTKDMNQLFKPNQTEVPGSSSSQEKDLKM 491

  Fly   499 L---FPDRVRHKNLQSPQNSPLHQ------------TVPLEFDNEGPSTSNQAQSSERRTGH--- 545
            .   .|.|...:.||......|||            |...|.:.:.|..:|    |:..||:
 Frog   492 FKFRKPRRPAKQTLQDSFQLDLHQDPEHGLESRLLVTDLAENEIQNPEETN----SKAETGNEGA 552

  Fly   546 ---EADTTLAVEQAVAQAGVEQDQGDEAEPIAPIRP--PIHSKTKNWYSGYCNRWASLLGAFTKL 605
               |.|.:...|...|:...|:.:||..  :|...|  .|...:.::|:.:||.|.:.|||...:
 Frog   553 EPTETDESDRGEDMEAEQPTEEQKGDST--VAQKVPEFEIQELSTSFYAKFCNHWVAFLGAILSI 615

  Fly   606 LVMLLVNWYYALTCFLVVFVVWFYVGTANPAVKPGLTAEFNFFAWLK---SVIFRCFGKRMNEYE 667
            ::|.::.|.|||....|..:::.|:|..||.:.||..|.|:||||::   ..:||    :....|
 Frog   616 VIMFVIQWIYALANLGVAIILYLYIGRVNPGLNPGAAANFSFFAWIRHGAQTLFR----KPRPKE 676

  Fly   668 QIVVTPSCPGVDLSPTQLNEQNEDFRPRPNYHHSSVI-EGRLID 710
            |.|||||...|.:..|||.|:||||..|..|||||:| :|:.||
 Frog   677 QFVVTPSLHSVGMETTQLTEENEDFASRGRYHHSSIITQGQFID 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12773	NP_001284773.1	2a30	88..>456	CDD:273347	195/368 (53%)
slc12a8	XP_031749017.1	2a30	6..>417	CDD:273347	199/379 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	379	1.000	Domainoid score	I840
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11628
Inparanoid	1	1.050	516	1.000	Inparanoid score	I1262
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D344013at33208
OrthoFinder	1	1.000	-	-		FOG0007328
OrthoInspector	1	1.000	-	-		oto105154
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5443
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.970