Protein Alignment MTPAP and TRF5

DIOPT Version :9

• Sequence 1: NP_001259129.1
• Gene: MTPAP / 31081
• FlyBaseID: FBgn0024360
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_014100.2
• Gene: TRF5 / 855417
• SGDID: S000005243
• Length: 642
• Species: Saccharomyces cerevisiae
• Alignment Length: 480
• Identity: 106/480 - (22%)
• Similarity: 190/480 - (39%)
• Gaps: 120/480 - (25%)

  Fly   160 QRHLLGLLRGAADIEEQVQQLYEHTRLNELGIRMRFLAALQVQQAIAGMFPAAQAQPFGSSVNGF 224
            ||.:...|  .::|::.|.  |.....||:..|.|.:..|  ::|:..::..|....|||.....
Yeast   169 QRRIADWL--TSEIKDFVH--YISPSKNEIKCRNRTIDKL--RRAVKELWSDADLHVFGSFATDL 227

  Fly   225 GRMGCDLDLILRFDSDMGAKIPLEAAVPSRLVYHTKENLSNGRSQTQRHMECFGDMLHLFLPGVC 289
            ...|.|:|.:                |.||  ...||: .|...:..||::..|..:.:.:
Yeast   228 YLPGSDIDCV----------------VNSR--NRDKED-RNYIYELARHLKNKGLAIRMEV---- 269

  Fly   290 HVRRILQARVPIIKYHHEHLDLEVDLSMSNLTGFYMSELLYMFGEMDPRVRPLTFTIRRWAQTCG 354
                |::.||||||:......|.:|:|.....|...::|:..:....|.:|.|...|:::..:..
Yeast   270 ----IVKTRVPIIKFIEPQSQLHIDVSFERTNGLEAAKLIREWLRDSPGLRELVLIIKQFLHSRR 330

  Fly   355 LTNPSPGRWISNFSLTCLVMFFLQQLRQPILPTIGALAKAAEPGDSRVTEDGINCTFTRNVDRLG 419
            |.|...| .:..|::.|||..||..                   ..|:..:.|:.     :|.||
Yeast   331 LNNVHTG-GLGGFTVICLVYSFLNM-------------------HPRIKSNDIDV-----LDNLG 370

  Fly   420 FRSRNQSSLSELLLQFFEFYSQ-FDFHNRAISLNEGK----PLS-----KPDHS--AMYIVNPLE 472
            .          ||:.|||.|.: |.:.:.|||:::|.    |.|     :|..|  ::.|.:|.:
Yeast   371 V----------LLIDFFELYGKNFGYDDVAISISDGYASYIPKSCWRTLEPSRSKFSLAIQDPGD 425

  Fly   473 QLLNVSK-NVSLEECERL---RIEVR-NAAWVLESEVENASVPEGDGQELSCGLLNLFKH----- 527
            ...|:|: :.::::.::.   ..|:. |..|    |:.:|:..:..|:.:   |.|:.|:
Yeast   426 PNNNISRGSFNMKDIKKAFAGAFELLVNKCW----ELNSATFKDRVGKSI---LGNVIKYRGQKR 483

  Fly   528 ---------PEKAVIRPNMFFKPR-MVEVSDLFEQKEAGATSSSTPPTPAITYKSASVRQQVQSI 582
                     ..||:|....:.|.| .:...|||      ...:...|...| ||.....::.|..
Yeast   484 DFNDERDLVQNKAIIENERYHKRRTRIVQEDLF------INDTEDLPVEEI-YKLDEPAKKKQKA 541

  Fly   583 KAATR-SELKQLRGSGSSVPTSSPN 606
            |...| .|:|:     |::|:..|:
Yeast   542 KKDKREGEIKK-----SAIPSPPPD 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTPAP	NP_001259129.1	NT_PAP_TUTase	193..333	CDD:143392	31/139 (22%)
		PAP_assoc	427..477	CDD:281779	17/61 (28%)
TRF5	NP_014100.2	TRF4	100..611	CDD:227585	106/480 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810