Protein Alignment MTPAP and TUT4

DIOPT Version :9

• Sequence 1: NP_001259129.1
• Gene: MTPAP / 31081
• FlyBaseID: FBgn0024360
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_005270733.1
• Gene: TUT4 / 23318
• HGNCID: 28981
• Length: 1652
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 77/275 - (28%)
• Similarity: 130/275 - (47%)
• Gaps: 35/275 - (12%)

  Fly   217 FGSSVNGFGRMGCDLDLILRFDSDMGAKIPLEAAVPSRLVYHTKENLSNGRSQTQRHMECFGDML 281
            ||||.||||....|||:.:..:....|:           ..:.||.:.|.....:||
Human   996 FGSSKNGFGFRDSDLDICMTLEGHENAE-----------KLNCKEIIENLAKILKRH-------- 1041

  Fly   282 HLFLPGVCHVRRILQARVPIIKYHHEHLDLEVDLSMSNLTGFYMSELLYMFGEMDPRVRPLTFTI 346
                ||:.::..|..|:|||:|:.|....||.|:|:.|....:.:.:|..:..:||||:.|.:|:
Human  1042 ----PGLRNILPITTAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTM 1102

  Fly   347 RRWAQTCGLTNPSPGRWISNFSLTCLVMFFLQQLRQPILPTIGALAKAAEPGDSRVTEDGINCTF 411
            :.:|:.|.:.:.|.|. :|:::...:|::||||.:.|::|.:..:....:.....|  ||.|..|
Human  1103 KVFAKRCDIGDASRGS-LSSYAYILMVLYFLQQRKPPVIPVLQEIFDGKQIPQRMV--DGWNAFF 1164

  Fly   412 TRNVDRLGFR----SRNQSSLSELLLQFFEFYS-QFDFHNRAISLNEGKPLSKPD----HSAMYI 467
            ....:.|..|    .:|..||.||.|....||: :|||....||:.:.|.|:..:    ...:.|
Human  1165 FDKTEELKKRLPSLGKNTESLGELWLGLLRFYTEEFDFKEYVISIRQKKLLTTFEKQWTSKCIAI 1229

  Fly   468 VNPLEQLLNVSKNVS 482
            .:|.:...|:...||
Human  1230 EDPFDLNHNLGAGVS 1244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTPAP	NP_001259129.1	NT_PAP_TUTase	193..333	CDD:143392	32/115 (28%)
		PAP_assoc	427..477	CDD:281779	16/54 (30%)
TUT4	XP_005270733.1	NT_PAP_TUTase	375..487	CDD:143392
		PAP_assoc	628..677	CDD:281779
		NT_PAP_TUTase	971..1089	CDD:143392	32/115 (28%)
		PAP_assoc	1184..1237	CDD:281779	16/52 (31%)
		PTZ00368	<1280..1375	CDD:173561
		CytochromB561_N	1375..>1516	CDD:286826
		DUF1421	<1383..1650	CDD:284607
		FAM75	1423..>1484	CDD:291323

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810