Protein Alignment MTPAP and Tent4a

DIOPT Version :9

• Sequence 1: NP_001259129.1
• Gene: MTPAP / 31081
• FlyBaseID: FBgn0024360
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_006517250.1
• Gene: Tent4a / 210106
• MGIID: 2682295
• Length: 732
• Species: Mus musculus
• Alignment Length: 684
• Identity: 127/684 - (18%)
• Similarity: 219/684 - (32%)
• Gaps: 264/684 - (38%)

  Fly    16 RTYCIKHNASEAASPGRN----AGRPNYEEF-IGRHQRQAQCSIVVQVSSEKSYEELYNYCSSFG 75
            ||:....:.:..|.||..    ||.|...:| .||.:|:                   |..|::|
Mouse   146 RTFFSFADGAAHAHPGPRGSTPAGSPPQHQFHPGRRKRE-------------------NKASTYG 191

  Fly    76 SIMGAHHYCVRQDETLHYILLEYATSDEAAAAIGAGVTNGELS--GVPVRSPFLWFRAAGGGRRS 138
                           |:|:|    :...||...|.|....:.:  |.|.:|     ||     .|
Mouse   192 ---------------LNYLL----SGSRAATLSGGGGPGAQAARPGTPWKS-----RA-----YS 227

  Fly   139 PKLVANTAPALLSLDGTRQVDQRHLLGLLRGAADIEEQVQQLYEHTRLNELGIRMRFLAALQVQQ 203
            |                             |...:.|::...|...........||.....:::.
Mouse   228 P-----------------------------GIQGLHEEIIDFYNFMSPCPEEAAMRREVVKRIET 263

  Fly   204 AIAGMFPAAQAQPFGSSVNGFGRMGCDLDLILRFDSDMGAKIPLEAAVPSRLVYHTKENLSNGRS 268
            .:..::|.|..|.|||...|......|:||::....:......||.|:       .|.|::.
Mouse   264 VVKDLWPTADVQIFGSFSTGLYLPTSDIDLVVFGKWERPPLQLLEQAL-------RKHNVAE--- 318

  Fly   269 QTQRHMECFGDMLHLFLPGVCHVRRILQARVPIIKYHHEHLDLEVDLSMSNLTGFYMSELLYMFG 333
                               .|.::.:.:|.|||||...:..:::||:|.:..||...:|.:..:.
Mouse   319 -------------------PCSIKVLDKATVPIIKLTDQETEVKVDISFNMETGVRAAEFIKNYM 364

  Fly   334 EMDPRVRPLTFTIRRWAQTCGLTNPSPGRWISNFSLTCLVMFFLQQLRQPILPTIGALAKAAEPG 398
            :....:..|...::::.....|.....| .||::||..:.:.|||     :.|.|
Mouse   365 KKYSLLPYLILVLKQFLLQRDLNEVFTG-GISSYSLILMAISFLQ-----LHPRI---------- 413

  Fly   399 DSRVTEDGINCTFTRNVDRLGFRSRNQSSLSELLLQFFEFYSQ-FDFHNRAISLNEG-------- 454
            |:|                     |...:|..||::|||.|.: |::....|.:.||
Mouse   414 DAR---------------------RADENLGMLLVEFFELYGRNFNYLKTGIRIKEGGAYIAKEE 457

  Fly   455 ---------KP--------------LSKPDHSAM---------YIV------------------N 469
                     :|              :.:..:.||         |||                  :
Mouse   458 IMKAMTSGYRPSMLCIEDPLLPGNDVGRSSYGAMQVKQVFDYAYIVLSHAVSPLARSYPNRDSES 522

  Fly   470 PLEQLLNVSKNVSLEECERLRIEVRNAAWVLE---SEVENASVPEGDGQELSCGLLNLFKHPEKA 531
            .|.:::.|::.|         |:.|.  |:.|   |.:    :|..|       |.|..|..|:.
Mouse   523 TLGRIIKVTQEV---------IDYRR--WIKEKWGSRI----LPSPD-------LDNRIKIKERI 565

  Fly   532 VIRPNMFFKPRMVEVSDLFEQK-----------EAGATSSS------------TPPTPAITYKSA 573
            ........:.|  |.|..:.|:           .:|:::||            |.|.|.:.....
Mouse   566 TTCNGEQMQSR--EPSSPYTQRLTLSLSSPQLLSSGSSASSVSSLSGSDITRVTIPPPTLGVAPV 628

  Fly   574 SVRQQVQSIKAATRSELKQLRG-SGSSVPTSSPN 606
            ..||  ..:...|  .||.:.. :..::|::|||
Mouse   629 PCRQ--AGVDGTT--SLKAVHSVTSPAIPSASPN 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTPAP	NP_001259129.1	NT_PAP_TUTase	193..333	CDD:143392	30/139 (22%)
		PAP_assoc	427..477	CDD:281779	18/108 (17%)
Tent4a	XP_006517250.1	TRF4	233..>538	CDD:227585	68/379 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810