Protein Alignment MTPAP and F43E2.1

DIOPT Version :10

• Sequence 1: NP_569904.1
• Gene: MTPAP / 31081
• FlyBaseID: FBgn0024360
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_495546.2
• Gene: F43E2.1 / 185708
• WormBaseID: WBGene00018390
• Length: 467
• Species: Caenorhabditis elegans
• Alignment Length: 497
• Identity: 93/497 - (18%)
• Similarity: 175/497 - (35%)
• Gaps: 146/497 - (29%)

  Fly   163 LLGLLRG----AADIEEQVQQLYEHTRLNELGIRMRFLAALQVQQAIAGMFPAAQAQPFGSSVNG 223
            |..:|:|    ...:|:.:...|.:.|.::..:..|.|....|::.:.......|....|..:.|
 Worm    16 LKSILQGDHPSLKQLEQDINIFYMNQRQSQSMLEERKLYVALVRKYLKSEGVTKQLASQGIKLRG 80

  Fly   224 FGRMG-----C-----DLDLILRFDSDMGAK----IPLEAAVPSRLVYHTKENLSNGRSQTQRHM 274
            ....|     |     ||||.:...:....|    |.|:|..  |.:.::||.           .
 Worm    81 LSVFGSFPTHCASKDSDLDLCVCATATGNKKQLPVIILQAIF--RDMMYSKEG-----------Q 132

  Fly   275 ECFGDMLHLFLPGVCHVRRILQARVPIIKYHHEHLDLEVDLS-------MSNLTGFYMSELLYMF 332
            ..||:.:   :.|:..|:   .|:||||::...  |:.||||       .::|...|::    .:
 Worm   133 NIFGENV---VSGISFVQ---TAKVPIIRFKIN--DVPVDLSATFDDNPRTSLAAKYIN----AY 185

  Fly   333 GEMDPRVRPLTFTIRRWAQTCGLTNPSPGRWISNFSLTCLVMFFLQQLRQPILPTIGALAKAAEP 397
            .::|.|.:.|...:::|.::.|........:.:::|:..|::..||.  ..|||.:
 Worm   186 CQLDDRFKILVMFLKKWMKSEGRAEDHLRIYPNSYSIILLLIHVLQW--YDILPNL--------- 239

  Fly   398 GDSRVTEDGINCTFTRNVDRLGFRSRNQSSLSELLLQFFEFYSQFDFHNRAISLNEGKPLSKPDH 462
               ..|...:   |.|...:|       |.|:||..:|     :|......||::..:|.:.
 Worm   240 ---HQTHSDL---FHRGNFKL-------SDLAELRHEF-----KFPLDENTISMHRKRPSND--- 283

  Fly   463 SAMYIVNPLEQLLNVSKNVSLEECE--------RLRIEVRNAAWVLESEVENASVPEGDGQ---- 515
                        |.|.:.:.|..|:        ..|..:||      .|:|..|..:.|.|
 Worm   284 ------------LTVVQLLYLFACQYSNHVVLLNYRFNMRN------GEIEALSQKDQDYQITIL 330

  Fly   516 ---------ELSCGLLNLFKHPE---KAVIRPNMFFKPRMVEVSDLFEQKEAGATSSSTPPTPAI 568
                     ..:...|:|.|..|   ..:::|:......::|::       ...|.....|.|.:
 Worm   331 DAYDVRNPGRSARNALDLVKTLEALKSLLVQPHEGMFKTVMEIT-------RNRTYERVVPPPQV 388

  Fly   569 TYKS---------------ASVRQQVQSIKAATRSELKQLRG 595
            .|:.               .||..|....:.|...:::.::|
 Worm   389 LYQDYDMQFGADPYNMPLVGSVEYQQWLEQVAMHHQIQMMQG 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTPAP	NP_569904.1	NT_PAP_TUTase	193..333	CDD:143392	35/160 (22%)
		PAP_assoc	427..>461	CDD:427532	8/33 (24%)
F43E2.1	NP_495546.2	NT_PAP_TUTase	51..186	CDD:143392	35/159 (22%)