Protein Alignment MTPAP and usip-1

DIOPT Version :10

• Sequence 1: NP_569904.1
• Gene: MTPAP / 31081
• FlyBaseID: FBgn0024360
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_506056.1
• Gene: usip-1 / 179670
• WormBaseID: WBGene00014124
• Length: 662
• Species: Caenorhabditis elegans
• Alignment Length: 491
• Identity: 107/491 - (21%)
• Similarity: 182/491 - (37%)
• Gaps: 165/491 - (33%)

  Fly    87 QDETLHYILLEYATSDEA------AAAIGAGVTNGELSGVPVRSPFLWFRAAGGGRRSPKLVANT 145
            ||:   :::|:..:.|||      :.|.|..:.|.::...|
 Worm    62 QDQ---FMILQMESIDEANRICHDSIAKGFAINNTKIVFTP------------------------ 99

  Fly   146 APALLSLDGTRQVD--------QRH-----LLGLLRGAADIEEQVQQLYEHTRLNELGIRMRFLA 197
               ||.|:|.|..|        |.|     ||.:|..|.     .|:|.|..::.|.|...
 Worm   100 ---LLGLNGFRLQDAIDFMKTSQPHFNNDELLEVLTMAI-----CQELPERLKILEDGFSF---- 152

  Fly   198 ALQVQQAIAGMFPAAQAQPFGSSVNGFGRMG-CDLDLILRFDSDMGAKI-----PLEAAV--PSR 254
               ::|.::.:...:..:.|||..:...|.| .|:|:.:...|..|.::     ||...|  |..
 Worm   153 ---IEQGVSELIQNSACEMFGSFASPVRRNGYSDIDINVESVSAPGQRVSTNVRPLNEVVANPKC 214

  Fly   255 LVYH--TKENL-----------------SNGRSQTQRHMECFGDMLHLFLPGVCHVRRILQARVP 300
            |:.|  ||..|                 .|...:|:..|                  |.|.||.|
 Worm   215 LITHPLTKSELETYPQEEIIKILYRCFNENSAFKTKFEM------------------RFLPARTP 261

  Fly   301 IIKYHH---EHLDLEVDLSMSNLTGFYMSELLYMFGEMD----PRVRPLTFTIRRWAQTCGLTNP 358
            ||.:.:   |.:::..|||:.|......:.||:.|...|    .|::.....|..||::..|.:
 Worm   262 IIVFKNIEVEGMNVSYDLSVHNQISVEKASLLHEFIVKDKSKGSRMKNAMMFIVHWAKSNKLLS- 325

  Fly   359 SPGRW----------ISNFSLTCLVMFFLQQLRQPILPTIGALAKAAEPGDSRVTE------DGI 407
              |.:          ::::.:..||:.|:|.....:  .:...||.    ||||.|      .|.
 Worm   326 --GDYPEEKLEVKTKLNSYIINQLVIHFVQAATNKV--HVNPQAKR----DSRVNEYNFDTLFGD 382

  Fly   408 NCTFTRNVDRLGFRSRNQSSLSELLLQFFEFYSQFDFHNRAI---SLNEGKPLSKP----DHSAM 465
            .|.|.|                    :.|::|:.|||.|:||   ...:.|.||..    :.|.:
 Worm   383 YCKFFR--------------------ELFKYYANFDFTNKAIYGKKAMQKKTLSSAHGGVEESPL 427

  Fly   466 YIVNPLEQLLNVSKNVSLEECERLRIEVRNAAWVLE 501
            .:::|::...|:|..|:.:..:.|...:|||.::|:
 Worm   428 MLMDPMDITHNISAKVTEDAVKLLNGLIRNALFILK 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTPAP	NP_569904.1	NT_PAP_TUTase	193..333	CDD:143392	36/169 (21%)
		PAP_assoc	427..>461	CDD:427532	11/40 (28%)
usip-1	NP_506056.1	NT_Pol-beta-like	142..297	CDD:472251	38/179 (21%)
		PAP_assoc	382..437	CDD:427532	16/74 (22%)