Protein Alignment MTPAP and pup-2

DIOPT Version :10

• Sequence 1: NP_569904.1
• Gene: MTPAP / 31081
• FlyBaseID: FBgn0024360
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_498100.1
• Gene: pup-2 / 175708
• WormBaseID: WBGene00019628
• Length: 508
• Species: Caenorhabditis elegans
• Alignment Length: 303
• Identity: 80/303 - (26%)
• Similarity: 139/303 - (45%)
• Gaps: 36/303 - (11%)

  Fly   194 RFLAALQVQQAIAGMFPA-AQAQPFGSSVNGFGRMGCDLDLILRFDSDMGAKIPLEAAVPSRLVY 257
            ||  ||::|..::..|.. .....:||:.||||...||:|:.|.|.             ||...:
 Worm   150 RF--ALEMQVHLSACFGCRVVLDIYGSTRNGFGTRFCDVDMSLSFS-------------PSPPSW 199

  Fly   258 HTKENLSNGRSQTQRHMECFGDMLHLFLPGVCHVRRILQARVPIIKYHHEHLDLEVDLSMSNLTG 322
            .|         .:.|.|......|..|...|  ..|.:.|:|||:::....:|:|.|:|..|...
 Worm   200 AT---------NSDRVMRAVAKALVDFPKAV--DERYVNAKVPIVRFRSSDMDMEADISYKNDLA 253

  Fly   323 FYMSELLYMFGEMDP-RVRPLTFTIRRWAQTCGLTNPSPGRWISNFSLTCLVMFFLQQLRQPILP 386
            .:.::||..:.:.|| |:..|...::.||:..|:.:.|.|. :|:::...:::.:|||: :|| |
 Worm   254 LHNTQLLQQYCKWDPERLPTLGVWVKAWAKRSGVGDASKGS-LSSYAWIVMLIHYLQQV-EPI-P 315

  Fly   387 TIGALAKAAEPGDSRVTEDGINCTFTRNVDRLGFRSRNQSSLSELLLQFFEFY-SQFDFHNRAIS 450
            .:..|.:........|...|.|..:.:.||....| |.::|:.:|.:.|.::| :.||:....|.
 Worm   316 VLPCLQEMNHQKSENVYVQGYNTYYWKFVDTARTR-RCRASVVDLFVGFLDYYATYFDYSTNVIQ 379

  Fly   451 LNEGKPLSKPDHSAMY---IVNPLEQLLNVSKNVSLEECERLR 490
            :...|...|||....|   |.:|.|...|:::.|.:...|.:|
 Worm   380 MVSKKLEFKPDRWCKYPMCIADPFETDHNLAQGVDMPMFEYIR 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTPAP	NP_569904.1	NT_PAP_TUTase	193..333	CDD:143392	37/139 (27%)
		PAP_assoc	427..>461	CDD:427532	9/34 (26%)
pup-2	NP_498100.1	NT_PAP_TUTase	163..264	CDD:143392	32/124 (26%)
		TRF4	<169..>414	CDD:227585	71/272 (26%)