Protein Alignment MTPAP and pup-3

DIOPT Version :10

• Sequence 1: NP_569904.1
• Gene: MTPAP / 31081
• FlyBaseID: FBgn0024360
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_491621.1
• Gene: pup-3 / 172207
• WormBaseID: WBGene00019082
• Length: 482
• Species: Caenorhabditis elegans
• Alignment Length: 366
• Identity: 82/366 - (22%)
• Similarity: 146/366 - (39%)
• Gaps: 98/366 - (26%)

  Fly   158 VDQRHLLGLLRGAADIEEQVQQLYEHTRLNELGIRMRFLAALQVQQAIAGMFPAAQAQPFGSSVN 222
            ||..|...|.:.||.....::|.|..:..                 .|.|.:||
 Worm    74 VDTHHQEPLRKAAAQFRAVMKQEYPDSTC-----------------FITGSYPA----------- 110

  Fly   223 GFGRMGCDLDLILRFDSDMGAKIP-LEAAVPSRLVYHTKENLSNGRSQTQRHMECFGDMLHLFLP 286
                 |.|   |...|.|...|:| ||.|.|...:...::.||           |:..:.
 Worm   111 -----GVD---IFSSDIDFTVKVPTLEGANPFLKLMQLRKELS-----------CYYTIF----- 151

  Fly   287 GVCHVRRILQARVPIIKYHHEHLDLEVDLSMSNLTGFYMSELLYMFGEMDPRVRPLTFTIRRWAQ 351
            ...:|::   ..:|:::..|....:.:|:::.|.|....::||..:.::|.|...|...::.||.
 Worm   152 SKAYVQK---GNIPVLQLMHAETKVSIDVTIDNDTSKRNTQLLAFYSQLDTRFPLLCKAMKAWAA 213

  Fly   352 TCGLTNPSPGRWISNFSLTCLVMFFLQQLR-----QPILPTIGALAKAAEPGDSRVTEDGINCTF 411
            :||:...|.|| :::|||..:::.:||.::     |.|.|.:.        ||..|.:|..   .
 Worm   214 SCGVEGASRGR-LNSFSLCLMLIHYLQTVQVLLNIQEIFPELN--------GDIVVEDDNY---M 266

  Fly   412 TRN-----VDRLGFR-SRNQSSLSELLLQFFEFYSQFDFHNRAISLNEGKPLSK----------- 459
            .|:     :::..|. ::|.|||:.|.:.|.::||:|:|....||:..|..|.|
 Worm   267 KRDLKIEILEKGAFDFNQNTSSLAVLFIGFMKYYSEFNFKWNWISIKHGNVLKKKWSKTRVPKNG 331

  Fly   460 -PDHSAMYIVNPLEQLLNVSKNVS-----LEECERLRIEVR 494
             |......:|  .:.||.:.:|.:     ....||:::|.|
 Worm   332 MPKDCRFIVV--ADPLLEIPRNCAGTVRQQNYMERIQLEFR 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTPAP	NP_569904.1	NT_PAP_TUTase	193..333	CDD:143392	26/140 (19%)
		PAP_assoc	427..>461	CDD:427532	13/45 (29%)
pup-3	NP_491621.1	TRF4	90..>374	CDD:227585	76/350 (22%)