Protein Alignment MTPAP and MTPAP

DIOPT Version :10

• Sequence 1: NP_569904.1
• Gene: MTPAP / 31081
• FlyBaseID: FBgn0024360
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_319519.5
• Gene: MTPAP / 1279775
• VectorBaseID: AGAMI1_007722
• Length: 634
• Species: Anopheles gambiae
• Alignment Length: 606
• Identity: 302/606 - (49%)
• Similarity: 391/606 - (64%)
• Gaps: 56/606 - (9%)

  Fly    39 YEEFIGRHQRQAQCSIVVQVSSEKSYEELYNYCSSFGSIMGAHHYCV--RQDETLHYILLEYATS 101
            ::..:...:.:|:.||:||||||:||.|||:|||.||:|..:|||.|  ..|...||||||:.:|
Mosquito    51 FDTMLSTRRAEARKSILVQVSSERSYNELYHYCSQFGTIQSSHHYRVDGDGDGDCHYILLEFGSS 115

  Fly   102 DEAAAAIGAGVTNGELSGVPVRSPFLWFRAAGGGRRSPKLVANTAP--ALLSLDGTRQVDQRHLL 164
            .||.||:.:||.:.|..||..||.|||||..    ..|||:|...|  :|..:|||:.:.:..|.
Mosquito   116 AEADAAMQSGVFSTERPGVRARSIFLWFRTG----PKPKLIAQEEPKRSLALIDGTQPIQEAELN 176

  Fly   165 GLLRGAADIEEQVQQLYEHTRLNELGIRMRFLAALQVQQAIAGMFPAAQAQPFGSSVNGFGRMGC 229
            |||..|..|::||..|:..|:||:||.|:||||..|::.::.||||.|.|.||||||||:|||||
Mosquito   177 GLLTAAESIDDQVTVLHRVTKLNDLGKRLRFLAVRQLESSLQGMFPQAVAHPFGSSVNGYGRMGC 241

  Fly   230 DLDLILRFDSDMGAKIPLEAAVPSRLVYHTKENLSNGRSQTQRHMECFGDMLHLFLPGVCHVRRI 294
            |||:|:..||..|.  |.:..  ||||||||....|.|:|.||.:|..||:|.||||||..||||
Mosquito   242 DLDVIMDLDSRSGE--PPDRT--SRLVYHTKATNPNERTQVQRQLESIGDVLQLFLPGVNSVRRI 302

  Fly   295 LQARVPIIKYHHEHLDLEVDLSMSNLTGFYMSELLYMFGEMDPRVRPLTFTIRRWAQTCGLTNPS 359
            |:|||||:||||||||||:||:|:|..|.|||||||:||::|.|||||||.:|||||:.||||.:
Mosquito   303 LKARVPIVKYHHEHLDLEIDLTMNNTAGVYMSELLYLFGQLDARVRPLTFCVRRWAQSVGLTNQT 367

  Fly   360 PGRWISNFSLTCLVMFFLQQLRQPILPTIGAL----AKAAEPGDSRVTEDGIN-----CTFTRNV 415
            ||.||:|||||.|||:|||||.:|:||:|..|    |.......:.||..|..     .||.:|.
Mosquito   368 PGYWITNFSLTMLVMYFLQQLARPVLPSINRLIQLSASCPPQTSAPVTRFGEGETEWAYTFLKNP 432

  Fly   416 DRLG-FRSRNQSSLSELLLQFFEFYSQFDFHNRAISLNEGKPLSKPDHSAMYIVNPLEQLLNVSK 479
            ...| |||.|:::|.:||:|||||||||||..||||||.|..:.|||||.||||||||.:|||||
Mosquito   433 SIYGSFRSENEATLEQLLVQFFEFYSQFDFSQRAISLNLGSTILKPDHSPMYIVNPLETVLNVSK 497

  Fly   480 NVSLEECERLRIEVRNAAWVLESEVENASVPEGDGQELSCGLLNLFKHPEKAVIRPNMFFKPRMV 544
            ||:|||.|..|::||||.|:||:..:....|..     ..||::||...::..|.|.|||..|::
Mosquito   498 NVNLEETELFRMQVRNAVWLLEAHGKETGAPTE-----PWGLVSLFGPKQQERITPQMFFTKRLL 557

  Fly   545 EVSDLFEQKEAGATSSSTPPTPAITYKSASVRQQVQSIKAATRSELKQL----------RGSGSS 599
            .|.|:|::..|.|      ||   .|::.:|:.||.:|:.||::||.:|          |..|..
Mosquito   558 NVKDIFDEVPADA------PT---QYRNPAVKSQVAAIQRATKAELHKLGAGGGGGNSNRTGGVE 613

  Fly   600 VPTSSP----------NNRRR 610
            ..||||          |.:||
Mosquito   614 PRTSSPMEGTGVKLKRNTKRR 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTPAP	NP_569904.1	NT_PAP_TUTase	193..333	CDD:143392	87/139 (63%)
		PAP_assoc	427..>461	CDD:427532	22/33 (67%)
MTPAP	XP_319519.5	None