Protein Alignment MTPAP and mkg-p

DIOPT Version :10

• Sequence 1: NP_569904.1
• Gene: MTPAP / 31081
• FlyBaseID: FBgn0024360
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_316693.4
• Gene: mkg-p / 1277247
• VectorBaseID: AGAMI1_002977
• Length: 700
• Species: Anopheles gambiae
• Alignment Length: 531
• Identity: 115/531 - (21%)
• Similarity: 199/531 - (37%)
• Gaps: 160/531 - (30%)

  Fly   156 RQVDQRHLLGLLRGAADIEEQ--------VQQLYEHTRLNELGIRM-RFLAALQVQQAIAGM--- 208
            |::......|..:||...:|:        :|.|.:.......|..| ..:||||...|...|
Mosquito    31 RRLSMNRKKGNKKGARKQQEEAGEPTSMLLQPLVQSLSTCAPGSEMSALIAALQPAPADVEMVLN 95

  Fly   209 -----------FPAAQA--QPFGSSVNGFGRMGCDLDLILRFDSDMGAKIPLEAAVPSRLVYHTK 260
                       .|..||  ..|||..:|......|||..:.:
Mosquito    96 MVKDDLNRVLNLPNNQATIYEFGSIKSGLLLKDSDLDFYIHY----------------------- 137

  Fly   261 ENLSNGRSQTQRHMECFGDMLHLFLPGVCHVR----------RILQARVPIIKYHHEHLDLEVDL 315
                 .|.:|:|..:.  .::|:    ||...          :||.|:||:::..|...:|:.|:
Mosquito   138 -----AREKTEREEQI--KLIHV----VCSRMDRDTSFTGKVKILGAKVPLLRAVHVRTNLQCDI 191

  Fly   316 SMSNLTGFYMSELLYMFGEMDPRVRPLTFTIRRWAQTCGLTNPSPGRWISNFSLTCLVMFFLQQL 380
            :.||..|.|.|:.::...:.|.|:..||..::.|||...:.  :....::::.|..:|:|:||..
Mosquito   192 NFSNARGCYNSKFIHAIMKFDERIHQLTVMVKFWAQCAHIL--TAHHQMNSYCLIMMVIFYLQTR 254

  Fly   381 RQPILPTIGALAKAAEPGDSRVTEDGINCTFTRNVDRLGFRSRNQSSLSELLLQFFEFYSQFDFH 445
            :.|::|::..|    :.|.:|:|....|..:.:.:.   :::.|.|::.|||:.||::||:|||.
Mosquito   255 KLPVIPSVEDL----QQGIARITFGPWNLGYPQQIQ---YKTWNVSTVRELLVGFFKYYSEFDFA 312

  Fly   446 NRAISLNEGKPLSK-----------------------PDHSA---MYIVNPLEQLLNVSK----N 480
            ...||...|:..|.                       |:.|.   :.|.:|.|..:||.|    |
Mosquito   313 GNIISPYVGRLCSTVELEKKSIRELAPYYRAVERENYPELSLGPFITIQDPFELNVNVGKVLRMN 377

  Fly   481 VSLEE-----------CERLRIEVRNAAWVLESEVENASVPEGDGQELSCGLLNLFKHPEKAVIR 534
            |..|:           |:|.:                       |.|.:..|:.||...:|.
Mosquito   378 VLAEQMKHSLKHAYELCQRFQ-----------------------GGEFAKLLVALFTDVQKC--- 416

  Fly   535 PNMFFKPRMVEVSDLFEQK---EAGA--TSSSTPPTPAITYKSASVRQQVQSIKAATRSELKQLR 594
                  |:.|:.|....:|   .|||  ....||    :...:...:||.....::|.|......
Mosquito   417 ------PKPVKESKAAAKKPTTNAGAKPAGGDTP----VANGTVVEKQQQPGPSSSTNSSSGSSS 471

  Fly   595 GSGSSVPTSSP 605
            .|.|:..|::|
Mosquito   472 TSNSNGSTAAP 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTPAP	NP_569904.1	NT_PAP_TUTase	193..333	CDD:143392	36/166 (22%)
		PAP_assoc	427..>461	CDD:427532	14/56 (25%)
mkg-p	XP_316693.4	None