DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MTPAP and Tent2

DIOPT Version :9

Sequence 1:	NP_001259129.1	Gene:	MTPAP / 31081	FlyBaseID:	FBgn0024360	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_001348466.1	Gene:	Tent2 / 100715	MGIID:	2140950	Length:	484	Species:	Mus musculus

Alignment Length:	335	Identity:	85/335 - (25%)
Similarity:	163/335 - (48%)	Gaps:	41/335 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 IEEQVQQLYEHTRLNELGIRMRFLAALQVQQAIAGMFPAAQAQPFGSSVNGFGRMGCDLDLILRF 237
            :.:|:.:|:|..:.....::.:.|...|:|:.|..:||.::....|||:||||....|.||.|..
Mouse   156 LSQQILELFETCQQQASDLKKKELCRAQLQREIQLLFPQSRLFLVGSSLNGFGARSSDGDLCLVV 220

  Fly   238 DSDMGAKIPLEAAVPSRLVYHTKENLSNGRSQTQRHMECFGDMLHLFLPGVCHVRRILQARVPII 302
            ..:           |.....:.|....:..:...:|. |      ..|.|.....::::|:|||:
Mouse   221 KEE-----------PCFFQVNQKTEARHILTLVHKHF-C------TRLSGYIERPQLIRAKVPIV 267

  Fly   303 KYHHEHLDLEVDLSMSNLTGFYMSELLYMFGEMDPRVRPLTFTIRRWAQTCGLTNPSPGRWISNF 367
            |:..:...:|.||:::|..|...:.||..:..::.|||||...|::||....:.:.|.|. :|::
Mouse   268 KFRDKVSCVEFDLNVNNTVGIRNTFLLRTYAYLENRVRPLVLVIKKWASHHDINDASRGT-LSSY 331

  Fly   368 SLTCLVMFFLQQLRQPILPTIGALAKAAEPGDSRVTEDGINCTFTRNVDRLGFRSRNQSSLSELL 432
            ||..:|:.:||.|.:||||::..:..     :|..|...::.......:...:.|:|:|||.:||
Mouse   332 SLVLMVLHYLQTLPEPILPSLQKIYP-----ESFSTSVQLHLVHHAPCNVPPYLSKNESSLGDLL 391

  Fly   433 LQFFEFY-SQFDFHNRAISLNEGKPLSKPD-----HSAMYIVNPLE-----------QLLNVSKN 480
            |.|.::| ::||::.:.||:.|.|.:.:||     :..:.:..|.:           |..::.|:
Mouse   392 LGFLKYYATEFDWNTQMISVREAKAIPRPDDMEWRNKYICVEEPFDGTNTARAVHEKQKFDMIKD 456

  Fly   481 VSLEECERLR 490
            ..|:..:||:
Mouse   457 QFLKSWQRLK 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MTPAP	NP_001259129.1	NT_PAP_TUTase	193..333	CDD:143392	35/139 (25%)
MTPAP	NP_001259129.1	PAP_assoc	427..477	CDD:281779	17/66 (26%)
Tent2	NP_001348466.1	Nuclear localization signal. /evidence=ECO:0000255	76..92
Tent2	NP_001348466.1	TRF4	121..>468	CDD:227585	85/335 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5260
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810