Protein Alignment MTPAP and mtpap

DIOPT Version :10

• Sequence 1: NP_569904.1
• Gene: MTPAP / 31081
• FlyBaseID: FBgn0024360
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_002940378.2
• Gene: mtpap / 100492805
• XenbaseID: XB-GENE-958512
• Length: 578
• Species: Xenopus tropicalis
• Alignment Length: 539
• Identity: 170/539 - (31%)
• Similarity: 268/539 - (49%)
• Gaps: 47/539 - (8%)

  Fly     1 MNSLVRRSAQQLSLWRTYCIKHNASEAASPGRN-------AGRPNYEEFIGRHQRQAQCSIVVQV 58
            :.|:||.:.:.||    ..:......||:.|..       ..|..:.|.....|.||:.::::..
 Frog    33 LRSVVRVTGRALS----NAVGGQQQVAAAAGGGLCLDEDPVTRRTFAEVQKERQEQAKHTVLINC 93

  Fly    59 SSEKSYEELYNYCSSFGSI--------MGAHHYCVRQDETLHYILLEYATSDEAAAAIGAGVTNG 115
            ....:..:...|.|..|.|        .|||       ..:.::..|...|..:|.::.. |.|.
 Frog    94 PPNVNENKFLKYLSQHGQITRHFFYEGYGAH-------AVVEFLDRESIESLRSATSLPT-VENE 150

  Fly   116 ELSGVPVRSPFLWFRAAGGGRRSPKLVANTAPALLSLDGTRQ--VDQRHLLGLLRGAADIEEQVQ 178
            .:  :|.:|            |...|.:::|...:.:...||  :....|:..|..|.:||||..
 Frog   151 CI--LPFKS------------RLFTLKSDSALGNVPVPCHRQTALPINELIQKLCKAQNIEEQAY 201

  Fly   179 QLYEHTRLNELGIRMRFLAALQVQQAIAGMFPAAQAQPFGSSVNGFGRMGCDLDLILRFDSDMGA 243
            .|.|..:|.:..||:|||.:..::......||.|...|:||:||.||::||||||.|..| |:..
 Frog   202 ALLEEYQLTDENIRLRFLVSSLIKDIATAYFPEATVNPYGSTVNSFGKLGCDLDLFLDLD-DIQK 265

  Fly   244 KIPLEAAVPSRLVYHTKENLSNGRSQTQRHMECFGDMLHLFLPGVCHVRRILQARVPIIKYHHEH 308
            :|.::...|....|..| .:.:.|..|||.:...|:.:..|.||...|::||.||.|::::.|:.
 Frog   266 RIAVKTTGPFATEYLIK-RVPSARVATQRILSVIGECIDNFGPGCTGVQKILNARCPLVRFSHQP 329

  Fly   309 LDLEVDLSMSNLTGFYMSELLYMFGEMDPRVRPLTFTIRRWAQTCGLTNPSPGRWISNFSLTCLV 373
            ..|:.||:..|......|||||::|..|.|:|.|.||:|.||:..|:|:..||.||:|||||.::
 Frog   330 AGLQCDLTSDNRIALRSSELLYIYGCFDHRLRALVFTLRCWARVHGITSAIPGAWITNFSLTMMI 394

  Fly   374 MFFLQQLRQPILPTIGALAKAAEPGDSRVTEDGINCTFTRNVDRLGFRSRNQSSLSELLLQFFEF 438
            :||||:...|::||:..|...|...|..:. ||.:|:|..|::|:. .|:|..:|..||.:||||
 Frog   395 LFFLQKRSPPVIPTLDHLKGLAGKEDKHII-DGHDCSFVSNLNRIK-PSQNSEALDVLLGEFFEF 457

  Fly   439 YSQFDFHNRAISLNEGKPLSKPDHSAMYIVNPLEQLLNVSKNVSLEECERLRIEVRNAAWVLESE 503
            |..|||....|.:.:||..:||:...:||.||.||.|||||||:..:.:|.....|.:||:::.:
 Frog   458 YGNFDFSKNCIDIRKGKEQNKPEVCPLYIRNPFEQTLNVSKNVNQSQLDRFVALARESAWIMQEQ 522

  Fly   504 VENASVPEGDGQELSCGLL 522
            :..:...|.....|...||
 Frog   523 ISQSVHKENTAWGLGTLLL 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MTPAP	NP_569904.1	NT_PAP_TUTase	193..333	CDD:143392	50/139 (36%)
		PAP_assoc	427..>461	CDD:427532	15/33 (45%)
mtpap	XP_002940378.2	RL	73..143	CDD:465510	14/76 (18%)
		NT_PAP_TUTase	216..354	CDD:143392	50/139 (36%)
		TRF4	<312..>513	CDD:227585	85/202 (42%)