Protein Alignment Tsp2A and CD53

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_000551.1
• Gene: CD53 / 963
• HGNCID: 1686
• Length: 219
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 59/225 - (26%)
• Similarity: 97/225 - (43%)
• Gaps: 44/225 - (19%)

  Fly    19 VKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIG-VYVLIGISIVMMAVSFL 82
            :||.||.||::.|:....:....::|.....|......|  .|..:| |:|::| ||:|: |:||
Human     9 LKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNL--PSLTLGNVFVIVG-SIIMV-VAFL 69

  Fly    83 GCLSALMENTLALFVFVGTQVFGFIAIVAGSAVLLQFSTINSSL---QPLLNVSLRGFVATSEYT 144
            ||:.::.||...|..|       ||.::   .:||...|:...|   :..||..:...:..|.:.
Human    70 GCMGSIKENKCLLMSF-------FILLL---IILLAEVTLAILLFVYEQKLNEYVAKGLTDSIHR 124

  Fly   145 YSNYVLT-----MIQENIGCCGATGPWDYLDLRQPLPSSCRDTVSGNAFFNGCVDEL-TWFFEGK 203
            |.:...|     .||..:.|||..|..|:..  .| |:||    ..:....||..:. .||...
Human   125 YHSDNSTKAAWDSIQSFLQCCGINGTSDWTS--GP-PASC----PSDRKVEGCYAKARLWFHSN- 181

  Fly   204 TGWIVALAMTLGLLNV-ICAV----MSFVL 228
                   .:.:|::.: :|.:    |||.|
Human   182 -------FLYIGIITICVCVIEVLGMSFAL 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	59/225 (26%)
CD53	NP_000551.1	Tetraspanin	9..208	CDD:459767	59/225 (26%)
		CD53_like_LEL	104..186	CDD:239417	20/96 (21%)