Protein Alignment Tsp2A and TSPAN10

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_114151.3
• Gene: TSPAN10 / 83882
• HGNCID: 29942
• Length: 355
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 61/271 - (22%)
• Similarity: 97/271 - (35%)
• Gaps: 90/271 - (33%)

  Fly    18 CVKYTLFCFNIVAWMISTALFALTVW---------------LRAEPGFNDWLRILEAQSFYIGVY 67
            ||||.:|..|....::.....|:.:|               |.|:|
Human    75 CVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPADP------------------- 120

  Fly    68 VLIGIS---IVMMAVSFLGCLSALMENTLALFVFVGTQVFGFIAI--VAGSAVLLQFSTINSSLQ 127
             ::|::   :|:.|||..|.|.||.|||..|..|.| .:..|:.:  |||:.|:..:..:..||:
Human   121 -MLGLALGGLVVSAVSLAGYLGALCENTCLLRGFSG-GILAFLVLEAVAGALVVALWGPLQDSLE 183

  Fly   128 PLLNVSLRGFVATSEYTYSNYVLTMIQENIGCCGATGPWD-----YLDLRQP------LPSSC-- 179
            ..|.|::..:....:.   .::|..:|..:.||||....|     |.:...|      ||:||
Human   184 HTLRVAIAHYQDDPDL---RFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCI 245

  Fly   180 ---RDTVSGN------------------AFFNGCVDEL-TWF---FEGKTGWIVALAMTLG---- 215
               .|..|.|                  .:..||...| .|.   .....|:.:|:.:..|
Human   246 DPREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELL 310

  Fly   216 ----LLNVICA 222
                ||..:.|
Human   311 LAARLLGALAA 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	60/270 (22%)
TSPAN10	NP_114151.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33
		Tetraspanin	76..226	CDD:459767	41/173 (24%)
		oculospanin_like_LEL	172..291	CDD:239420	24/121 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..355