Protein Alignment Tsp2A and Cd82

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_113985.2
• Gene: Cd82 / 83628
• RGDID: 69070
• Length: 266
• Species: Rattus norvegicus
• Alignment Length: 270
• Identity: 57/270 - (21%)
• Similarity: 112/270 - (41%)
• Gaps: 64/270 - (23%)

  Fly    17 GCV---KYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILE--AQSFYIGVYVLIGISIVM 76
            |||   ||.||.||::.:::...:....||:.|:.  :.::.:|:  :.|..:|.||.||:..:.
  Rat     4 GCVKVTKYFLFLFNLLFFILGAVILGFGVWILADK--SSFISVLQTSSSSLQVGAYVFIGVGAIT 66

  Fly    77 MAVSFLGCLSALMENTLALFVFVGTQVFGFIAIVA--GSAVLLQFSTI-------NSSLQPLLNV 132
            |.:.||||:.|:.|....|.::.   ||..:.::|  ...||..|:..       |:.:..:.|.
  Rat    67 MLMGFLGCIGAVNEVRCLLGLYF---VFLLLILIAQVTVGVLFYFNADKLKQEMGNTVMDIIQNY 128

  Fly   133 SLRGFVATSE-YTYSNYVLTMIQENIGCCGATGPWDYLDLRQPL---------PSSC-------- 179
            |:....:..| :.|       :|..:.|||...|.::  .|.|:         |.||
  Rat   129 SVNASSSREEAWDY-------VQAQVKCCGWVSPSNW--TRNPVLKNSTKTTYPCSCEKTKEEDN 184

  Fly   180 ------------RDTVSGNA------FFNGCVDELTWFFEGKTGWIVALAMTLGLLNVICAVMSF 226
                        ..|.|.|:      ...||:::...:.:...|.::.:...:.::.::...:|.
  Rat   185 QLIVKKGFCESDNSTASENSPEDWPVHPEGCMEKAQAWLQENFGILLGVCAGVAVIELLGLFLSI 249

  Fly   227 VLVQAVKKEE 236
            .|.:.:..|:
  Rat   250 CLCRYIHSED 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	54/260 (21%)
Cd82	NP_113985.2	Tetraspanin	24..253	CDD:459767	47/242 (19%)
		CD37_CD82_like_LEL	106..228	CDD:239413	21/130 (16%)