Protein Alignment Tsp2A and tspan5

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: NP_001072198.1
• Gene: tspan5 / 779644
• XenbaseID: XB-GENE-868310
• Length: 268
• Species: Xenopus tropicalis
• Alignment Length: 257
• Identity: 58/257 - (22%)
• Similarity: 108/257 - (42%)
• Gaps: 46/257 - (17%)

  Fly    18 CVKYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIGVYVLIGISIVMMAVSFL 82
            |:||.:|.||::.|::......:.:|..:|.|....:..:.....:..|::.:.:..||..:.|.
 Frog    14 CIKYFIFGFNVIFWLLGITFLGVGLWAWSEKGVLSNISSITDLGGFDPVWLFLVVGGVMFILGFA 78

  Fly    83 GCLSALMENTLAL---FVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLNVSLRGFVATSEYT 144
            ||:.||.|||..|   .||:|  :..|:.:.||....:....|...||..:|.::|.:  ..:..
 Frog    79 GCIGALRENTFLLKFFSVFLG--IIFFLELTAGVLAFVFKDWIKDQLQFFINNNIRAY--RDDID 139

  Fly   145 YSNYVLTMIQENIGCCGATGPWDY-LDL------------RQPLPSSC------RDTVSGNAFFN 190
            ..| ::...||...||||.|..|: |::            |..:|.||      .|.::....::
 Frog   140 LQN-LIDFTQEYWQCCGAFGADDWNLNIYFNCTDANASRERCGVPFSCCTKDPAEDVINTQCGYD 203

  Fly   191 ----------------GCVDELTWFFEGKTGWIVALAMTLGLLNV--ICAVMSFVL-VQAVK 233
                            |||.:...:.:.....:..:.:.:.||.:  ||...:.|. ::||:
 Frog   204 VRQKPELDQQETIHTKGCVPQFEKWLQDNLTIVAGVFIGIALLQIFGICLAQNLVSDIEAVR 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	55/251 (22%)
tspan5	NP_001072198.1	Tetraspanin	15..258	CDD:459767	54/247 (22%)
		TM4SF9_like_LEL	113..233	CDD:239412	23/122 (19%)