Protein Alignment Tsp2A and Tspan17

DIOPT Version :10

• Sequence 1: NP_525037.1
• Gene: Tsp2A / 31080
• FlyBaseID: FBgn0024361
• Length: 244
• Species: Drosophila melanogaster
• Sequence 2: XP_006517477.1
• Gene: Tspan17 / 74257
• MGIID: 1921507
• Length: 281
• Species: Mus musculus
• Alignment Length: 270
• Identity: 68/270 - (25%)
• Similarity: 112/270 - (41%)
• Gaps: 47/270 - (17%)

  Fly     6 GASDEQLEKQIGCV-KYTLFCFNIVAWMISTALFALTVWLRAEPGFNDWLRILEAQSFYIGVYVL 69
            |...:..:.::||. ||.||.||||.|::.....|:.:|...|.|....:..|........|::.
Mouse     3 GKHQQFQDPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLF 67

  Fly    70 IGISIVMMAVSFLGCLSALMENTLAL---FVFVGTQVFGFIAIVAGSAVLLQFSTINSSLQPLLN 131
            :.:..||..:.|.||:.||.|||..|   .||:|. :| |:.:.||....:....|...|...:|
Mouse    68 VVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGL-IF-FLELAAGILAFVFKDWIRDQLNLFIN 130

  Fly   132 VSLRGFVATSEYTYSNYVLTMIQENIGCCGATGPWDY--------LDL-----RQPLPSSC--RD 181
            .:::.:  ..:....| ::...||...||||.||.|:        .||     |..:|.||  ||
Mouse   131 NNVKAY--RDDLDLQN-LIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRD 192

  Fly   182 TV--------------------SGNAFFNGCVDELTWFFEGKTGWIVALAMTLGLLNV--ICAVM 224
            ..                    .|:.:..|||.:...:.:.....:..:.:.:.||.:  :|...
Mouse   193 PAEDVLNTQCGYDIRLKLELEQQGSIYTKGCVGQFEKWLQDNLIVVAGVLVGIALLQIFGLCLAQ 257

  Fly   225 SFVL-VQAVK 233
            :.|. ::|||
Mouse   258 NLVSDIKAVK 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp2A	NP_525037.1	Tetraspanin	19..230	CDD:459767	62/252 (25%)
Tspan17	XP_006517477.1	Tetraspanin	18..260	CDD:459767	61/246 (25%)
		TM4SF9_like_LEL	115..235	CDD:239412	25/122 (20%)